Evidence map›Paper›PMID 26461967›Full record

ReviewNature reviews. Cardiology2015

Environmental factors in cardiovascular disease.

Kristen E Cosselman, Ana Navas-Acien, Joel D Kaufman

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 237 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
237citing papers in PubMed, 8 pooled it
21.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

237 citing papers in PubMed, 8 syntheses or guidelines pooled it, 616 citations in OpenAlex.

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  15. PMEnvironment & health (Washington, D.C.) · 2026
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177 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kristen E CosselmanDepartment of Environmental and Occupational Health Sciences, University of Washington, 4225 Roosevelt Way Northeast, Suite 100, Seattle, WA 98105, USA.
Ana Navas-AcienDepartment of Environmental Health Sciences, Johns Hopkins University, 615 North Wolfe Street, Room W7513D, Baltimore, MD 21205, USA.
Joel D KaufmanDepartment of Environmental and Occupational Health Sciences, University of Washington, 4225 Roosevelt Way Northeast, Suite 100, Seattle, WA 98105, USA.
Northeast Health · USJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Environmental exposure is an important but underappreciated risk factor contributing to the development and severity of cardiovascular disease (CVD). The heart and vascular system are highly vulnerable to a number of environmental agents--ambient air pollution and the metals arsenic, cadmium, and lead are widespread and the most-extensively studied. Like traditional risk factors, such as smoking and diabetes mellitus, these exposures advance disease and mortality via augmentation or initiation of pathophysiological processes associated with CVD, including blood-pressure control, carbohydrate and lipid metabolism, vascular function, and atherogenesis. Although residence in highly polluted areas is associated with high levels of cardiovascular risk, adverse effects on cardiovascular health also occur at exposure levels below current regulatory standards. Considering the widespread prevalence of exposure, even modest contributions to CVD risk can have a substantial effect on population health. Evidence-based clinical and public-health strategies aimed at reducing environmental exposures from current levels could substantially lower the burden of CVD-related death and disability worldwide.

Indexed as

Primary PreventionAir PollutantsCardiovascular DiseasesEnvironmental ExposureHumansIncidenceMetalsRisk FactorsAir PollutantsMetals

Identifiers

PMID26461967
OpenAlexW1859890772

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.