ArticleBritish journal of cancer2015
The impact of patient comorbidity on cancer stage at diagnosis.
Article in British journal of cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 1 of them a synthesis that pooled it.
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Who cites it
76 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Impact of Morbidity and Disability on Attendance at Organized Breast Cancer-Screening Programs: A Systematic Review and Meta-Analysis.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022Pooled it
- Advancing care coordination to enhance shared care for complex cancer survivors in primary care (ACCESS-PC): protocol for a hybrid type 3 effectiveness-implementation trial.BMC primary care · 2026Article
- Diabetes mellitus is associated with earlier detection of posterior uveal melanoma.European journal of ophthalmology · 2026Article
- Article
- Comorbidity Burden in Lung Cancer and Malignant Pleural Mesothelioma: Nationwide Database Results of Turkey.Medicina (Kaunas, Lithuania) · 2026Article
- Age, Frailty, and Comorbidity as Predictors of Mortality and Failure to Rescue After Gastrointestinal Cancer Surgery: A National Retrospective Cohort Study.World journal of surgery · 2026Article
- The impact of anxiety and affective disorders on breast cancer screening in women in Puerto Rico.PloS one · 2026Article
- Effects of the COVID-19 pandemic and 'Find Cancer Early' campaign on cancer symptom knowledge in regional Western Australia.Journal of public health (Oxford, England) · 2025Article
- Article
- Radiation therapy for lung cancer in Aotearoa New Zealand.Cancer causes & control : CCC · 2025Article
- Liver Metastasis Risk and Timing in Pancreatic Cancer Patients Using Electronic Health Records.medRxiv : the preprint server for health sciences · 2025Article
- Unveiling trends in urinary tract cancer mortality among older adults in the United States (1999-2022): a CDC WONDER perspective.International urology and nephrology · 2025Article
- National variation in the treatment of lung cancer in a universal healthcare context.British journal of cancer · 2025Article
- Impact of Hypertension on Cancer Stage at Diagnosis Among French Women: The E3N Prospective Cohort.Cancer medicine · 2025Observational
- Comorbidity burden and risk of second primary non-breast cancer in breast cancer survivors.Cancer epidemiology · 2025Article
- Advanced risk signature analysis of inflammation markers in predicting prostate cancer using the Swedish Apolipoprotein-related MOrtality RISk (AMORIS) cohort.ESMO real world data and digital oncology · 2025Article
- "But if you don't know what my needs are, you can't help me": Health seeking experiences of older Black and Latinx cancer survivors.Journal of cancer policy · 2025Article
- Screen-detected breast cancer and cancer stage by area-level deprivation: a descriptive analysis using data from the National Cancer Registry Ireland.European journal of public health · 2025Article
- The association between the mental health disorders, substance abuse, and tobacco use with head & neck cancer stage at diagnosis.Cancer causes & control : CCC · 2025Article
- Longitudinal Trends of Comorbidities and Survival Among Kidney Cancer Patients in Asian Population.Cancer medicine · 2024Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt is known that cancer stage is affected by comorbidity, but the evidence regarding the magnitude and even direction of this effect is highly inconsistent and poorly understood. The aims of this study were to establish the impact of comorbidity on cancer stage at diagnosis, using both specific individual comorbid conditions and a global measure of comorbidity; and to assess whether this impact varied by cancer site, level of comorbidity burden and individual comorbidity type.
methodsWe examined comorbidity among 14,096 patients with breast, colon, rectal, liver, stomach, ovarian, uterine, bladder or kidney cancer. Patients were identified from cancer registry data, and then linked to hospitalisation data to determine the presence of comorbidity in the 5 years preceding cancer diagnosis. Individual comorbid conditions were identified using ICD-10 codes, and overall burden of comorbidity attributed using a cancer-specific measure of comorbidity (C3 Index).
resultsWe observed that the presence of patient comorbidity (a) increases the odds of being diagnosed with distant metastases, (b) does not lead to earlier diagnosis and (c) increases the likelihood of a patient receiving no stage of disease at diagnosis.
conclusionsPatient comorbidity has a substantial impact on cancer stage at diagnosis; however, this impact varies considerably by cancer type, individual comorbid condition and overall comorbidity burden.
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