TR2/TR4 overexpression in a humanized sickle cell disease mouse model decreases RBC adhesion to VCAM-1.
Jennell C White, Amrita Pawar, Gratiana Fu, Shuaiying Cui, Fitz Tavernier, Mariam Hamid, David Harro, Donald Giacherio, Andrew D Campbell, Patrick C Hines
Article in Blood cells, molecules & diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
2 citing papers in PubMed, 4 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
10 authors at 3 institutions in 1 country.
Jennell C WhiteWayne State University School of Medicine, Department of Pediatrics, United States.
Amrita PawarC. S. Mott Children's Hospital, Division of Pediatric Hematology/Oncology, United States.
Gratiana FuC. S. Mott Children's Hospital, Division of Pediatric Hematology/Oncology, United States.
Shuaiying CuiUniversity of Michigan Medical School, Department of Cell and Developmental Biology, United States.
Fitz TavernierC. S. Mott Children's Hospital, Division of Pediatric Hematology/Oncology, United States.
Mariam HamidC. S. Mott Children's Hospital, Division of Pediatric Hematology/Oncology, United States.
David HarroUniversity of Michigan Medical School, Department of Pathology, United States.
Donald GiacherioUniversity of Michigan Medical School, Department of Pathology, United States.
Andrew D CampbellC. S. Mott Children's Hospital, Division of Pediatric Hematology/Oncology, United States.
Patrick C HinesWayne State University School of Medicine, Department of Pediatrics, United States; Wayne State University School of Medicine, Department of Physiology, United States; Children's Hospital of Michigan, Division of Pediatric Critical Care Medicine, United States. Electronic address: phines@med.wayne.edu.
C. S. Mott Children's Hospital · USUniversity of Michigan · USWayne State University · US
Funding
Proteolytic Regulation of Troponin T & Cardiac FunctionR01HL098945 · NHLBI · WAYNE STATE UNIVERSITY · PI JIN, JIAN-PING · 2010 to 2014
$2.0M
Transgenic Analysis of Beta Globin SwitchingK01HL080954 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CAMPBELL, ANDREW D · 2005 to 2009
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
TR2/TR4 overexpression in a humanized sickle cell disease mouse model decreases RBC adhesion to VCAM-1. · full record | OpenQuestion