Evidence map›Paper›PMID 26459902›Full record

ArticleAntimicrobial agents and chemotherapy2016

Cooccurrence of Multiple AmpC β-Lactamases in Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis in Tunisia.

Thouraya Chérif, Mabrouka Saidani, Dominique Decré, Ilhem Boutiba-Ben Boubaker, Guillaume Arlet

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Detection of plasmid-mediated AmpC β-lactamases inIranian journal of microbiology · 2023
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  12. Plasmids carrying DHA-1 β-lactamases.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2018
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Thouraya ChérifUniversité de Tunis El Manar, Faculté de Médecine de Tunis, LR99ES09 Laboratoire de Résistance aux Antimicrobiens, Tunis, Tunisie.
Mabrouka SaidaniUniversité de Tunis El Manar, Faculté de Médecine de Tunis, LR99ES09 Laboratoire de Résistance aux Antimicrobiens, Tunis, Tunisie CHU Charles Nicolle, Service de Microbiologie, Tunis, Tunisia.
Dominique DecréSorbonne Université, UPMC Université Paris 06 CR7, Paris, France INSERM U1135, CIMI, Team E13, Paris, France AP-HP, Groupe Hospitalier des Hôpitaux Universitaires de l'Est Parisien, Département de Bactériologie, Paris, France.
Ilhem Boutiba-Ben BoubakerUniversité de Tunis El Manar, Faculté de Médecine de Tunis, LR99ES09 Laboratoire de Résistance aux Antimicrobiens, Tunis, Tunisie CHU Charles Nicolle, Service de Microbiologie, Tunis, Tunisia.
Guillaume ArletSorbonne Université, UPMC Université Paris 06 CR7, Paris, France INSERM U1135, CIMI, Team E13, Paris, France AP-HP, Groupe Hospitalier des Hôpitaux Universitaires de l'Est Parisien, Département de Bactériologie, Paris, France guillaume.arlet@tnn.aphp.fr.
Centre d'Immunologie et des Maladies Infectieuses · FRHôpital Charles-Nicolle · TNTunis El Manar University · TNTunis University · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over a period of 40 months, plasmid-mediated AmpC β-lactamases were detected in Tunis, Tunisia, in 78 isolates (0.59%) of Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis. In 67 isolates, only one ampC gene was detected, i.e., blaCMY-2-type (n = 33), blaACC (n = 23), blaDHA (n = 6) or blaEBC (n = 5). Multiple ampC genes were detected in 11 isolates, with the following distribution: blaMOX-2, blaFOX-3, and blaCMY-4/16 (n = 6), blaFOX-3 and blaMOX-2 (n = 3), and blaCMY-4 and blaMOX-2 (n = 2). A great variety of plasmids carrying these genes was found, independently of the species and the bla gene. If the genetic context of blaCMY-2-type is variable, that of blaMOX-2, reported in part previously, is unique and that of blaFOX-3 is unique and new.

Indexed as

AminoglycosidesAnti-Bacterial AgentsBacterial ProteinsBase Sequencebeta-LactamasesDrug Resistance, BacterialEnterobacteriaceae InfectionsEscherichia coliGene ExpressionHumansKlebsiella pneumoniaeMicrobial Sensitivity TestsMolecular Sequence DataPenicillinsPlasmidsProteus mirabilisAminoglycosidesAmpC beta-lactamasesAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesPenicillinsVirulence Factors

Identifiers

PMID26459902
PMCPMC4704229
OpenAlexW2200581355

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.