ArticleAntimicrobial agents and chemotherapy2015
Tigecycline Lock Therapy for Catheter-Related Bloodstream Infection Caused by KPC-Producing Klebsiella pneumoniae in Two Pediatric Hematological Patients.
Article in Antimicrobial agents and chemotherapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 13 citations in OpenAlex.
- Is an oritavancin catheter lock solution active against biofilms of staphylococci and enterococci?Heliyon · 2025Article
- A Dalbavancin Lock Solution Can Reduce Enterococcal Biofilms After Freezing.Infectious diseases and therapy · 2022Article
- Article
- Tigecycline treatment in a liver transplant infant with carbapenem-resistant Escherichia coli infection: Case report.Medicine · 2019Article
- Preliminary experience of tigecycline treatment for infection in children with hematologic malignancies.International journal of clinical pharmacy · 2018Article
- Preliminary experience with tigecycline treatment for severe infection in children.European journal of pediatrics · 2018Article
- Role of Lock Therapy for Long-Term Catheter-Related Infections by Multidrug-Resistant Bacteria.Antimicrobial agents and chemotherapy · 2018Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Catheter-related bacteremias carry high mortality rates in hematological patients. When a multidrug-resistant microorganism is involved, the catheter should ideally be removed; however, this approach is not always possible. Tigecycline lock therapy was used in two pediatric oncohematological patients with intravascular catheter-related infection due to KPC-producing Klebsiella pneumoniae. The catheter was salvaged in both cases, and the patients were later discharged. Our experience suggests the usefulness of this approach in treating this type of infection.
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