Evidence map›Paper›PMID 26459876›Full record

ArticleScientific reports2015

Association of Renal Function and Menopausal Status with Bone Mineral Density in Middle-aged Women.

Yueh-Hsuan Sheng, Jen-Hau Chen, Jeng-Min Chiou, Keh-Sung Tsai, Yue-Yuan Lee, Chwen-Keng Tsao, Yen-Ching Chen

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Yueh-Hsuan ShengDepartment of Family Medicine, Renai Branch, Taipei City Hospital, Taipei, Taiwan.
Jen-Hau ChenDepartment of Geriatrics and Gerontology, National Taiwan University Hospital, Taipei, Taiwan.
Jeng-Min ChiouInstitute of Statistical Science Academia Sinica, Taipei, Taiwan.
Keh-Sung TsaiDepartment of Internal Medicine and Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Yue-Yuan LeeInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan.
Chwen-Keng TsaoMJ Health Management Institution, Taipei, Taiwan.
Yen-Ching ChenInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan.
National Taiwan University · TWNational Taiwan University Hospital · TWInstitute of Statistical Science, Academia Sinica · TWTaipei City Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The association between mild renal dysfunction and bone mineral density (BMD) has not been fully explored. It is also unclear how menopausal status and the use of Chinese herb affect this association. This is a cross-sectional study that included a total of 1,419 women aged 40 to 55 years old who were recruited from the MJ Health Management Institution in Taiwan between 2009 and 2010. Spinal BMD was assessed by dual-energy X-ray absorptiometry. Renal function was assessed using estimated glomerular filtration rate (eGFR) and creatinine clearance rate (CCr). The multivariable logistic regression and general linear models were employed to assess the association between renal function and BMD. Stratification analyses were performed by menopausal status and use of Chinese herbs. Low CCr levels were significantly associated with low BMD [adjusted odds ratio (AOR) = 1.48, 95% confidence interval (CI) = 1.15-1.90]. This association was observed in premenopausal women (AOR = 1.43, 95% CI = 1.07-1.92) and in women not taking Chinese herbs (AOR = 1.48, 95% CI = 1.14-1.94). CCr is a better predictor for low BMD in middle-aged women. Menopausal status and the use of Chinese herbs also affected this association.

Indexed as

Bone DensityMenopauseAdultCreatinineCross-Sectional StudiesDrugs, Chinese HerbalFemaleGlomerular Filtration RateHumansKidneyKidney Function TestsMiddle AgedOsteoporosisPublic Health SurveillanceRisk FactorsTaiwanCreatinineDrugs, Chinese Herbal

Identifiers

PMID26459876
PMCPMC4602276
OpenAlexW2404834315

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.