Evidence map›Paper›PMID 26459685›Full record

ReviewSleep medicine2016

Sleep characteristics and cardiovascular risk in children and adolescents: an enumerative review.

Karen A Matthews, Elizabeth J M Pantesco

Abstract readReview
In one paragraph

Review in Sleep medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 4 pooled it
13.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 4 syntheses or guidelines pooled it, 132 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Lifelong Exercise as a Modulator of CD4European journal of clinical investigation · 2026
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Parental Exposure to Work Schedule Instability and Child Sleep Quality.Work, employment & society : a journal of the British Sociological Association · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Observational
  19. Article
  20. The impact of dietary and sleep rhythms on blood pressure in children and adolescents: a cross-sectional study.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Karen A MatthewsDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: matthewska@upmc.edu.
Elizabeth J M PantescoDepartment of Psychology, Rowan University, NJ, USA.
Rowan University · USUniversity of Pittsburgh · US

Funding

Development of Psychobiological Risk Factors in AdolescenceR01HL025767 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MATTHEWS, KAREN · 1985 to 2011
$4.3M
NHLBI NIH HHS HL025767NHLBI NIH HHS R01 HL025767
6 · The paper itself

Abstract

Cardiovascular risk factors develop in childhood and adolescence. This enumerative review addresses whether sleep characteristics, including sleep duration, continuity, quality, and daytime sleepiness, are associated with cardiovascular risk factors in young people. Thirty-nine studies were identified, which examined the following risk factors: metabolic syndrome, glucose and insulin, lipids, blood pressure, and cardiovascular responses to psychological stressors. Due to the availability of other reviews, 16 longitudinal studies of obesity published in 2011 and later were also included in this report. Excluded from the review were studies of participants with suspected or diagnosed sleep disorders and reports from sleep deprivation experiments. Combining studies, evidence was strongest for obesity, followed by glucose, insulin, blood pressure (especially ambulatory blood pressure), and parasympathetic responses to psychological stressors. There was little evidence for metabolic syndrome cluster, lipids, and blood pressure responses to psychological stressors. The more positive associations were obtained for studies that incorporated objective measures of sleep and that included adolescents. The foundational evidence is almost entirely cross-sectional, except for work on obesity. In summary, available evidence suggests that the associations between sleep characteristics and cardiovascular risk vary by risk factor. It is time to conduct studies to determine antecedent and consequent relationships, and to expand risk factors to include markers of inflammation.

Indexed as

AdolescentBlood PressureCardiovascular DiseasesChildHumansInsulinMetabolic SyndromeObesityRisk FactorsSleepSleep Wake DisordersInsulinBlood pressureCardiovascular risk factorsChildrenLipidsObesitySleep

Identifiers

PMID26459685
PMCPMC4689674
OpenAlexW772711389

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.