ArticleBMC pulmonary medicine2015
Patterns of heart rate variability and cardiac autonomic modulations in controlled and uncontrolled asthmatic patients.
Article in BMC pulmonary medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Trial
- Heart Rate Variability Applications in Medical Specialties: A Narrative Review.Applied psychophysiology and biofeedback · 2025Review
- Heart Rate Variability in Subjects with Severe Allergic Background Undergoing COVID-19 Vaccination.Vaccines · 2023Article
- Influence of Nicotine from Diverse Delivery Tools on the Autonomic Nervous and Hormonal Systems.Biomedicines · 2022Article
- Heart Rate Modeling and Prediction Using Autoregressive Models and Deep Learning.Sensors (Basel, Switzerland) · 2021Article
- Report of prenatal maternal demoralization and material hardship and infant rhinorrhea and watery eyes.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2020Article
- Indicators of metabolic syndrome in normotensive normoglycemic asthmatic patients.Journal of clinical and translational research · 2020Article
- The Dynamic Relationship Between Asthma and Obesity in Schoolchildren.American journal of epidemiology · 2020Article
- A Personalized Signature and Chronotherapy-Based Platform for Improving the Efficacy of Sepsis Treatment.Frontiers in physiology · 2019Review
- Associations between Parasympathetic Activity in the Month after Birth and Wheeze at Age 2-3 Years.American journal of respiratory and critical care medicine · 2018Article
- Maternal Heart Rate Variability during the First Stage of Labor.Frontiers in physiology · 2017Article
- Effect of Fasting Blood Glucose Level on Heart Rate Variability of Healthy Young Adults.PloS one · 2016Article
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1 author.
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Abstract
backgroundPrevious heart rate variability (HRV) studies in asthmatic subjects (AS) demonstrate predominance of parasympathetic drive concomitant with low HRV, which is against the general belief that enhanced parasympathetic modulation improves HRV. The aim of this study was to compare patterns of HRV and cardiac autonomic modulations of AS to healthy control subjects (HS).
methodsEighty AS and forty HS were enrolled in the study. Asthma control test and spirometry were used to discriminate uncontrolled (UA) from controlled (CA) asthmatic patients. Natural logarithmic (Ln) scale of total power (TP), very low frequency (VLF), low frequency (LF) and high frequency (HF) were used to evaluate HRV. Normalized low frequency (LF Norm) and high frequency (HF Norm) were used to determine sympathetic and parasympathetic autonomic modulations respectively.
resultsCA patients achieved significantly higher LnTP, LnLF, LnHF and HF Norm but lower LF Norm and LnLF/HF compared with UA patients (p < 0.05). Although CA patients showed increased HRV and augmented vagal modulation compared with HS, these findings were no longer significant following adjustment for mean heart rates and anti-asthma treatment. All measured HRV parameters were not significantly different in UA patients compared with the HS (p > 0.05).
conclusionsCA is associated with enhanced parasympathetic modulations and higher HRV compared with UA. However, neither CA nor UA patients had different autonomic modulations and/or HRV compared with HS.
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