Evidence map›Paper›PMID 26459310›Full record

SynthesisTumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine2016

CD20-negative diffuse large B cell lymphoma: a comprehensive analysis of 695 cases.

Jing Li, Shu Zhao, Jingxuan Wang, Jingyu Chen, Wen Wen, Qingyuan Zhang

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. A rare case of CD20JAAD case reports · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Plasmablastic Lymphoma of the Endometrium: A Rare Site for Primary Presentation.Journal of obstetrics and gynaecology of India · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Plasmablastic lymphoma: current perspectives.Blood and lymphatic cancer : targets and therapy · 2018
    Review
  16. Article
  17. Article
  18. Primary Nodal Unclassifiable CD20 Negative Diffuse Large B-cell Lymphoma With DualClinical pathology (Thousand Oaks, Ventura County, Calif.)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Jing LiDepartment of Internal Medicine, The Third Affiliated Hospital of Harbin Medical University, Haping Road 150 of Nangang District, Harbin, Heilongjiang Province, 150081, China.
Shu ZhaoDepartment of Internal Medicine, The Third Affiliated Hospital of Harbin Medical University, Haping Road 150 of Nangang District, Harbin, Heilongjiang Province, 150081, China.
Jingxuan WangDepartment of Internal Medicine, The Third Affiliated Hospital of Harbin Medical University, Haping Road 150 of Nangang District, Harbin, Heilongjiang Province, 150081, China.
Jingyu ChenDepartment of Internal Medicine, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, 150081, China.
Wen WenDepartment of Anesthesia, The Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Province, 541001, China.
Qingyuan ZhangDepartment of Internal Medicine, The Third Affiliated Hospital of Harbin Medical University, Haping Road 150 of Nangang District, Harbin, Heilongjiang Province, 150081, China. zqy77123@163.com.
Harbin Medical University · CNThird Affiliated Hospital of Harbin Medical University · CNFourth Affiliated Hospital of Harbin Medical University · CNGuilin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD20 expression is absent in a variety of diffuse large B cell lymphomas (DLBCLs), including plasmablastic lymphoma, primary effusion lymphoma, anaplastic lymphoma, kinase-positive DLBCL, and large B cell lymphoma arising in human herpesvirus 8-associated multicentric Castleman disease. These rare and heterogeneous tumors are characterized by the presence of proliferating immunoblasts with similar transcriptional profiles as those of plasma cells and are typically associated with highly aggressive pathologies, with high levels of chemotherapy resistance and low survival rates; thus, they pose significant diagnostic and treatment challenges. We conducted a systematic literature review of the limited existing clinical data to summarize the current knowledge regarding the biological basis, diagnostic limits, and potential therapeutic targets of distinct variants of CD20-negative DLBCL. This review will hopefully increase the awareness of these rare disorders among clinicians and pathologists and prompt basic and clinical research.

Indexed as

AdolescentAdultAgedAged, 80 and overAntigens, CD20Antineoplastic Combined Chemotherapy ProtocolsChildChild, PreschoolFemaleHumansInfantKaplan-Meier EstimateLymphoma, Large B-Cell, DiffuseMaleMiddle AgedOutcome Assessment, Health CareAntigens, CD20ALK-positive DLBCLCD20-negativeMulticentric Castleman diseasePlasmablastic lymphomaPrimary effusion lymphoma

Identifiers

PMID26459310
OpenAlexW1954818626

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.