Evidence map›Paper›PMID 26459200›Full record

ReviewClinical cardiology2016

Ranolazine in Cardiac Arrhythmia.

Marwan Saad, Ahmed Mahmoud, Islam Y Elgendy, C Richard Conti

Open access · bronzeAbstract readReview
In one paragraph

Review in Clinical cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. Predicting human cardiac QT alterations and pro-arrhythmic effects of compounds with a 3D beating heart-on-chip platform.Toxicological sciences : an official journal of the Society of Toxicology · 2023
    Article
  4. Review
  5. Article
  6. Sodium channel biophysics, late sodium current and genetic arrhythmic syndromes.Pflugers Archiv : European journal of physiology · 2017
    Review
  7. Review
  8. Article
  9. Advancements in pharmacotherapy for angina.Expert opinion on pharmacotherapy · 2017
    Review
  10. Optimization of anFrontiers in physiology · 2017
    Article
  11. Ranolazine is an Effective and Safe Treatment of Adults with Symptomatic Premature Ventricular Contractions due to Triggered Ectopy.The International journal of angiology : official publication of the International College of Angiology, Inc · 2016
    Article
  12. Experimental and early investigational drugs for angina pectoris.Expert opinion on investigational drugs · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Marwan SaadDepartment of Medicine, Seton Hall University School of Health and Medical Sciences, Trinitas Regional Medical Center, Elizabeth, New Jersey.
Ahmed MahmoudDepartment of Medicine, University of Florida, Gainesville, Florida.
Islam Y ElgendyDivision of Cardiovascular Medicine, University of Florida, Gainesville, Florida.ORCID http://orcid.org/0000-0001-9853-7591
C Richard ContiDivision of Cardiovascular Medicine, University of Florida, Gainesville, Florida.
University of Florida · USSeton Hall University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ranolazine utilization in the management of refractory angina has been established by multiple randomized clinical studies. However, there is growing evidence showing an evolving role in the field of cardiac arrhythmias. Multiple experimental and clinical studies have evaluated the role of ranolazine in prevention and management of atrial fibrillation, with ongoing studies on its role in ventricular arrhythmias. In this review, we will discuss the pharmacological, experimental, and clinical evidence behind ranolazine use in the management of various cardiac arrhythmias.

Indexed as

Action PotentialsAnimalsAnti-Arrhythmia AgentsArrhythmias, CardiacHeart Conduction SystemHeart RateHumansKineticsRanolazineSodium Channel BlockersSodium ChannelsTreatment OutcomeAnti-Arrhythmia AgentsRanolazineSodium Channel BlockersSodium Channels

Identifiers

PMID26459200
PMCPMC6490811
OpenAlexW1935709356

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.