Evidence map›Paper›PMID 26459155›Full record

Observational studyPharmacology, biochemistry, and behavior2015

Nicotine and carbon monoxide exposure from inhalation of cigarillo smoke.

Bartosz Koszowski, Zachary R Rosenberry, Alieu Kanu, Lauren C Viray, Jennifer L Potts, Wallace B Pickworth

Open access · greenAbstract readComparative StudyObservational Study
In one paragraph

Observational study in Pharmacology, biochemistry, and behavior, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Five-Day Changes in Biomarkers of Exposure Among Adult Smokers After Completely Switching From Combustible Cigarettes to a Nicotine-Salt Pod System.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020
    Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Characterizing #Backwoods on Instagram: "The Number One Selling All Natural Cigar".International journal of environmental research and public health · 2020
    Article
  12. Article
  13. Biomarkers of Exposure among U.S. Adult Cigar Smokers: Population Assessment of Tobacco and Health (PATH) Study Wave 1 (2013-2014).Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2019
    Article
  14. Article
  15. Article
  16. Cigarettes, Little Cigars, and Cigarillos: Initiation, Motivation, and Decision-Making.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2018
    Article
  17. An Ecological Momentary Assessment of Cigarette and Cigar Dual Use Among African American Young Adults.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2018
    Article
  18. Article
  19. Large Cigars: Smoking Topography and Toxicant Exposure.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Bartosz KoszowskiBattelle Memorial Institute, Battelle Public Health Center for Tobacco Research, Baltimore, MD, United States. Electronic address: koszowskib@battelle.org.
Zachary R RosenberryBattelle Memorial Institute, Battelle Public Health Center for Tobacco Research, Baltimore, MD, United States.
Alieu KanuBattelle Memorial Institute, Battelle Public Health Center for Tobacco Research, Baltimore, MD, United States.
Lauren C VirayBattelle Memorial Institute, Battelle Public Health Center for Tobacco Research, Baltimore, MD, United States.
Jennifer L PottsBattelle Memorial Institute, Battelle Public Health Center for Tobacco Research, Baltimore, MD, United States.
Wallace B PickworthBattelle Memorial Institute, Battelle Public Health Center for Tobacco Research, Baltimore, MD, United States.
Battelle · US

Funding

Mainstream Smoke Composition and Toxin Exposure from Prototypical Cigar ProductsR01CA158045 · NCI · BATTELLE CENTERS/PUB HLTH RES & EVALUATN · PI PICKWORTH, WALLACE BRUCE · 2012 to 2014
$2.1M
NCI NIH HHS 1R01CA158045-01A1NCI NIH HHS R01 CA158045
6 · The paper itself

Abstract

backgroundThere has been an increase in the use of cigarillos in the US. People who smoke cigarillos typically also regularly smoke cigarettes (dual users).

methodsWe compared puffing topography, biomarkers of acute exposure [exhaled carbon monoxide (COex) and plasma nicotine] and physiologic effects from usual brand cigarette and Black & Mild cigarillo smoking in dual users (N=23) in two laboratory sessions.

resultsParticipants (21 men) smoked an average of 17.5cigarettes/day. Cigarillo consumption varied widely from as few as 1/week to daily. Participants were highly nicotine dependent (average FTND score: 6.3). There were statistically significant differences in smoking behavior between cigarette and cigarillo smoking in time to smoke, number of puffs, and total puff volume (all P<0.001). Average puff duration, interpuff interval average puff volume, and puff velocity did not differ between cigarettes and cigarillos. Nicotine boost was similar after both cigarettes and cigarillos. COex boost was significantly greater after cigarillo smoking compared to cigarette smoking (P<0.001).

conclusionsThe smoking pattern and exposure profile indicate that dual users inhale cigarillo smoke just as they inhale cigarette smoke thereby exposing themselves to considerable amounts of nicotine and other components of tobacco smoke. COex exposure results imply that cigarillo smoking may be associated with higher exposure to smoke-delivered volatile components of mainstream cigarillo smoke including carcinogens when compared to cigarettes. IMPACT: The findings that cigarillos and cigarettes are smoked similarly in dual users are relevant to health and regulatory considerations on cigar products.

Indexed as

RespirationTobacco ProductsAdministration, InhalationAdolescentAdultAgedBiomarkersCarbon MonoxideCarcinogensFemaleHumansMaleMiddle AgedNicotineSmokeSmokingBiomarkersCarbon MonoxideCarcinogensNicotineSmokeBiomarkersCigarillosCigarsExposureTopography

Identifiers

PMID26459155
PMCPMC4662635
OpenAlexW2180555147

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.