ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2015
Surgical treatment of sacral chordoma: survival and prognostic factors.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Cervical chordomas: multicenter case series and meta-analysis.Journal of neuro-oncology · 2021Pooled it
- Surgical management of chordoma: A systematic review.The journal of spinal cord medicine · 2020Pooled it
- Assessing an Automated Noncontrast CT-based Pipeline for Sacral Tumor Classification Using a Hip Bone Reference Frame.Radiology. Imaging cancer · 2026Article
- Nomograms to predict lung metastasis in malignant primary osseous spinal neoplasms and cancer-specific survival in lung metastasis subgroup.Frontiers in oncology · 2024Article
- Analysis of morbidity and mortality in patients with primary bone tumors who underwent sacrectomy: A systematic review.Journal of bone oncology · 2022Review
- Outcomes of Surgery for Sacral Chordoma and Impact of Complications: A Report of 50 Consecutive Patients With Long-Term Follow-Up.Global spine journal · 2021Article
- LncRNA NONHSAT114552 Sponges miR-320d to Promote Proliferation and Invasion of Chordoma Through Upregulating NRP1.Frontiers in pharmacology · 2021Article
- A case-control study of computer navigation assisted resection of primary sacral chordoma above sacrum 3 level.Journal of bone oncology · 2020Article
- Conditional survival and changing risk profile in patients with chordoma: a population-based longitudinal cohort study.Journal of orthopaedic surgery and research · 2019Article
- Comparison of radiomics machine-learning classifiers and feature selection for differentiation of sacral chordoma and sacral giant cell tumour based on 3D computed tomography features.European radiology · 2019Article
- Defining preoperative imaging findings of sacral chordomas associated with decreased overall survival and local recurrence.Journal of spine surgery (Hong Kong) · 2019Article
- Role of the Apparent Diffusion Coefficient as a Predictor of Tumor Progression in Patients with Chordoma.AJNR. American journal of neuroradiology · 2018Article
- The Michel Benoist and Robert Mulholland yearly European Spine Journal Review: a survey of the "surgical and research" articles in the European Spine Journal, 2017.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2018Review
- Recurrence and survival factors analysis of 171 cases of sacral chordoma in a single institute.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2017Article
- Letter to the Editor concerning "Surgical treatment of sacral chordoma: survival and prognostic factors" by C. Ruosi et al. (Eur Spine J; 2015; 24(Suppl 7):S912-S917.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2017Article
- Whole-transcriptome analysis of chordoma of the skull base.Virchows Archiv : an international journal of pathology · 2016Article
- Health-Related Quality of Life After Spine Surgery for Primary Bone Tumour.Current treatment options in oncology · 2016Review
- Adjuvant gamma knife surgery and image-guided, intensity-modulated radiation therapy for the treatment of sacral chordomas.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation OncologyArticle
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionSacral chordoma is a rare low-to-intermediate grade malignant tumour. The mainstay of treatment is still surgery with en bloc and wide resection margins, which can grant the best chances of a long-term control or cure of this disease. The first aim of this paper is to collect data about survival, time to local recurrence and metastasis among patients affected by sacral chordoma and primarily treated with surgery. The second aim is to analyze the influence of level resection, tumor volume and surgical margins on local recurrence. MATERIALS AND
methodsThe study population was composed of 14 patients treated with sacral chordoma resection at the National Tumour Institute of Naples-Pascale (Italy) from January 2000 to June 2013. The median follow-up was 84 months (range 24-132 months). The follow-up was characterized by: standard radiographs, MRI, and a CT scan of the chest annually. Time to recurrence or metastasis was calculated from the date of resection to the date of diagnosis of first recurrence or metastasis.
resultsOut of all the patients, six died (42.86 %) during the follow-up; 6 (42.86 %) had local recurrence; 4 (28.57 %) had metastasis. At univariate analysis wide surgical margins (R0) were associated with increased survival up to a local recurrence (OR = 0.0286; 95 % CI = 0.0014-0.5739; P = 0.026); the level of resection (OR = 3.33; 95 % CI = 0.3619-30.7025; P = 0.592) and tumour volume (P = 1) did not show a statistically significant correlation. DISCUSSION: Based on our experience, we hope all patients to be treated by surgery, the only good standard treatment of this disease. The resection should result in margins as wide as possible. For these reasons, it is essential for this disease to be treated in highly specialized centres because only a complete surgery can offer a chance to care for these patients.
conclusionsSolid survival at long-term follow-up can be achieved by a surgical resection performed with wide margins.
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