Evidence map›Paper›PMID 26458883›Full record

ReviewPediatric nephrology (Berlin, Germany)2016

Toxic environmental exposures and kidney health in children.

Darcy K Weidemann, Virginia M Weaver, Jeffrey J Fadrowski

Abstract readReview
In one paragraph

Review in Pediatric nephrology (Berlin, Germany), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  19. The First Thousand Days: Kidney Health and Beyond.Healthcare (Basel, Switzerland) · 2021
    Review
  20. Emerging role of air pollution in chronic kidney disease.Environmental science and pollution research international · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Darcy K WeidemannDivision of Pediatric Nephrology, Children's Mercy Hospital, 2401 Gillham Rd, Kansas City, MO, 64108, USA. dkweidemann@cmh.edu.
Virginia M WeaverDepartment of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Jeffrey J FadrowskiWelch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, MD, USA.

Funding

RENAL DISEASE EPIDEMIOLOGY TRAINING GRANTT32DK007732 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI CREWS, DEIDRA CANDICE · 1995 to 2024
$7.7M
NIDDK NIH HHS T32 DK007732
6 · The paper itself

Abstract

High-level exposures to a number of agents are known to have direct nephrotoxic effects in children. A growing body of literature supports the hypothesis that chronic, relatively low-level exposure to various nephrotoxicants may also increase the risk for chronic kidney disease (CKD) or accelerate its progression. In this review we highlight several environmental nephrotoxicants and their association with CKD in children and adolescents. We also discuss unique epidemiological challenges in the use of kidney biomarkers in environmental nephrotoxicology.

Indexed as

AdolescentAristolochic AcidsChildDisease ProgressionDysuriaEnvironmental ExposureHumansKidneyMetals, HeavyMycotoxinsPrevalenceRenal Insufficiency, ChronicTriazinesaristolochic acid IAristolochic AcidsmelamineMetals, HeavyMycotoxinsTriazinesAristolochic acidArsenicCadmiumChronic kidney diseaseEnvironmental nephrotoxicantsLeadMelamine

Identifiers

PMID26458883
PMCPMC4829489

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.