ArticleScientific reports2015
Experimental verification and molecular basis of active immunization against fungal pathogens in termites.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 80 citations in OpenAlex.
- miR-701 modulates the humoral immune response of Coptotermes formosanus against Metarhizium anisopliae.Insect science · 2025Article
- Uncovering the function of insulin receptor substrate in termites' immunity through active immunization.Journal of insect science (Online) · 2024Article
- Assessment of bacterial communities ofFrontiers in microbiology · 2024Article
- Defensive behavior is linked to altered surface chemistry following infection in a termite society.Scientific reports · 2023Article
- Trade-offs between immunity and competitive ability in fighting ant males.BMC ecology and evolution · 2023Article
- The effect of ergosterol on the allogrooming behavior of termites in response to the entomopathogenic fungus Metarhizium anisopliae.Insect science · 2023Article
- Transcriptomic dissection of termite gut microbiota following entomopathogenic fungal infection.Frontiers in physiology · 2023Article
- Prophenoloxidase ofInternational journal of molecular sciences · 2022Article
- Differential Proteomics Analysis Unraveled Mechanisms ofInsects · 2022Article
- Transglutaminase 3 negatively regulates immune responses on the heart of the mosquito, Anopheles gambiae.Scientific reports · 2022Article
- A High Soldier Proportion Encouraged the Greater Antifungal Immunity in a Subterranean Termite.Frontiers in physiology · 2022Article
- Experimentally measured group direct benefits according to worker density explain group living of the termiteEcology and evolution · 2021Article
- Termites and Chinese agricultural system: applications and advances in integrated termite management and chemical control.Insect science · 2021Review
- Microbial Response to Fungal Infection in a Fungus-Growing Termite,Frontiers in microbiology · 2021Article
- Behaviours indicating cannibalistic necrophagy in ants are modulated by the perception of pathogen infection level.Scientific reports · 2020Article
- Biological Control of Tomato Gray Mold Caused byPathogens (Basel, Switzerland) · 2020Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Termites are constantly exposed to many pathogens when they nest and forage in the field, so they employ various immune strategies to defend against pathogenic infections. Here, we demonstrate that the subterranean termite Reticulitermes chinensis employs active immunization to defend against the entomopathogen Metarhizium anisopliae. Our results showed that allogrooming frequency increased significantly between fungus-treated termites and their nestmates. Through active social contact, previously healthy nestmates only received small numbers of conidia from fungus-treated individuals. These nestmates experienced low-level fungal infections, resulting in low mortality and apparently improved antifungal defences. Moreover, infected nestmates promoted the activity of two antioxidant enzymes (SOD and CAT) and upregulated the expression of three immune genes (phenoloxidase, transferrin, and termicin). We found 20 differentially expressed proteins associated with active immunization in R. chinensis through iTRAQ proteomics, including 12 stress response proteins, six immune signalling proteins, and two immune effector molecules. Subsequently, two significantly upregulated (60S ribosomal protein L23 and isocitrate dehydrogenase) and three significantly downregulated (glutathione S-transferase D1, cuticle protein 19, and ubiquitin conjugating enzyme) candidate immune proteins were validated by MRM assays. These findings suggest that active immunization in termites may be regulated by different immune proteins.
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