Evidence map›Paper›PMID 26458367›Full record

ArticleMonash bioethics review

Ethical aspects of creating human-nonhuman chimeras capable of human gamete production and human pregnancy.

César Palacios-González

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Monash bioethics review. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

César Palacios-GonzálezInstitute for Science Ethics and Innovation, The University of Manchester, Room 3.383, Stopford Building, Oxford Road, Manchester, M13 9PL, UK. Cesar.palaciosgonzalez@postgrad.manchester.ac.uk.
University of Manchester · GB

Funding

Wellcome Trust wt 087439/z/08/z
6 · The paper itself

Abstract

In this paper I explore some of the moral issues that could emerge from the creation of human-nonhuman chimeras (HNH-chimeras) capable of human gamete production and human pregnancy. First I explore whether there is a cogent argument against the creation of HNH-chimeras that could produce human gametes. I conclude that so far there is none, and that in fact there is at least one good moral reason for producing such types of creatures. Afterwards I explore some of the moral problems that could emerge from the fact that a HNH-chimera could become pregnant with a human conceptus. I focus on two sets of problems: problems that would arise by virtue of the fact that a human is gestated by a nonhuman creature, and problems that would emerge from the fact that such pregnancies could affect the health of the HNH-chimera.

Indexed as

Ethics, MedicalEthics, ResearchMoralsAbortion, EugenicAnimalsBiotechnologyChimeraFemaleGametogenesisHumansInfant, NewbornOocyte DonationPregnancyReproductive Techniques, AssistedStem Cell ResearchWrongful LifeBiotechnologyChimerasHuman gametesHuman–nonhuman chimerasPart humanXenopregnancy

Identifiers

PMID26458367
PMCPMC4631712
OpenAlexW2190826822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.