Evidence map›Paper›PMID 26457555›Full record

ArticleNature neuroscience2015

Neural mechanisms supporting maladaptive food choices in anorexia nervosa.

Karin Foerde, Joanna E Steinglass, Daphna Shohamy, B Timothy Walsh

Abstract read
In one paragraph

Article in Nature neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Optimizing relapse prevention and changing habits (REACH+) in anorexia nervosa.The International journal of eating disorders · 2022
    Trial
  7. Review
  8. Different brain regions support deliberation during food choice in disordered and healthy eating.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Recent developments in treatments for eating disorders.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Review
  14. Avoidance habit learning in adolescents and young women with anorexia nervosa: an fMRI study.Journal of child psychology and psychiatry, and allied disciplines · 2026
    Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review

47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Karin FoerdePsychology Department, New York University, New York, New York, USA.
Joanna E SteinglassDivision of Clinical Therapeutics, New York State Psychiatric Institute, New York, New York, USA.
Daphna ShohamyDepartment of Psychology, Zuckerman Mind Brain Behavior Institute, and Kavli Institute for Brain Science, Columbia University, New York, New York, USA.
B Timothy WalshDivision of Clinical Therapeutics, New York State Psychiatric Institute, New York, New York, USA.

Funding

Translational Research on Eating Disorders: Reward SystemsR01MH079397 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI WALSH, B. TIMOTHY · 2008 to 2012
$2.8M
Neural Mechanisms of Food Choice in Anorexia NervosaR01MH105452 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI SHOHAMY, DAPHNA, STEINGLASS, JOANNA E · 2015 to 2018
$2.3M
Cognitive Neuroscience of Anorexia NervosaK23MH076195 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI STEINGLASS, JOANNA E · 2007 to 2011
$886k
NIMH NIH HHS K23 MH076195NIMH NIH HHS R01 MH079397NIMH NIH HHS R01 MH105452
6 · The paper itself

Abstract

People routinely make poor choices, despite knowledge of negative consequences. The authors found that individuals with anorexia nervosa, who make maladaptive food choices to the point of starvation, engaged the dorsal striatum more than healthy controls when making choices about what to eat, and that activity in fronto-striatal circuits was correlated with their actual food consumption in a meal the next day.

Indexed as

Food PreferencesAdaptation, PhysiologicalAnorexia NervosaCorpus StriatumDecision MakingHumansNerve NetStarvation

Identifiers

PMID26457555
PMCPMC4624561

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.