Evidence map›Paper›PMID 26457303›Full record

ArticleBioMed research international2015

Comparative Study of Anterior Eye Segment Measurements with Spectral Swept-Source and Time-Domain Optical Coherence Tomography in Eyes with Corneal Dystrophies.

Anna K Nowinska, Sławomir J Teper, Dominika A Janiszewska, Anita Lyssek-Boron, Dariusz Dobrowolski, Robert Koprowski, Edward Wylegala

Open access · hybridAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Corneal dystrophies.Nature reviews. Disease primers · 2020
    Review
  6. [Corneal dystrophies in optical coherence tomography].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2019
    Article
  7. Article
  8. Review
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anna K NowinskaOphthalmology Clinic, Medical University of Silesia, 40-760 Katowice, Poland ; Department of Ophthalmology, Saint Barbara Hospital, 41-200 Sosnowiec, Poland.
Sławomir J TeperOphthalmology Clinic, Medical University of Silesia, 40-760 Katowice, Poland.
Dominika A JaniszewskaOphthalmology Clinic, Medical University of Silesia, 40-760 Katowice, Poland ; Department of Ophthalmology, Saint Barbara Hospital, 41-200 Sosnowiec, Poland.
Anita Lyssek-BoronDepartment of Ophthalmology, Saint Barbara Hospital, 41-200 Sosnowiec, Poland.
Dariusz DobrowolskiOphthalmology Clinic, Medical University of Silesia, 40-760 Katowice, Poland ; Department of Ophthalmology, Saint Barbara Hospital, 41-200 Sosnowiec, Poland.
Robert KoprowskiDepartment of Biomedical Computer Systems, University of Silesia, Sosnowiec, Poland.
Edward WylegalaOphthalmology Clinic, Medical University of Silesia, 40-760 Katowice, Poland.
Medical University of Silesia · PLUniversity of Silesia in Katowice · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare anterior eye segment measurements and morphology obtained with two optical coherence tomography systems (TD OCT, SS OCT) in eyes with corneal dystrophies (CDs).

methodsFifty healthy volunteers (50 eyes) and 54 patients (96 eyes) diagnosed with CD (epithelial basement membrane dystrophy, EBMD = 12 eyes; Thiel-Behnke CD = 6 eyes; lattice CD TGFBI type = 15 eyes; granular CD type 1 = 7 eyes, granular CD type 2 = 2 eyes; macular CD = 23 eyes; and Fuchs endothelial CD = 31 eyes) were recruited for the study. Automated and manual central corneal thickness (aCCT, mCCT), anterior chamber depth (ACD), and nasal and temporal trabecular iris angle (nTIA, tTIA) were measured and compared with Bland-Altman plots.

resultsGood agreement between the TD and SS OCT measurements was demonstrated for mCCT and aCCT in normal individuals and for mCCT in the CDs group. The ACD, nTIA, and tTIA measurements differed significantly in both groups. TBCD, LCD, and FECD caused increased CCT. MCD caused significant corneal thinning. FECD affected all analyzed parameters.

conclusionsBetter agreement between SS OCT and TD OCT measurements was demonstrated in normal individuals compared to the CDs group. OCT provides comprehensive corneal deposits analysis and demonstrates the association of CD with CCT, ACD, and TIA measurements.

Indexed as

AdolescentAdultAnterior Eye SegmentCase-Control StudiesCorneal Dystrophies, HereditaryFemaleHumansMaleMiddle AgedTomography, Optical Coherence

Identifiers

PMID26457303
PMCPMC4589615
OpenAlexW1826572301

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.