SynthesisBioMed research international2015
Coagulation Parameters and Risk of Progressive Hemorrhagic Injury after Traumatic Brain Injury: A Systematic Review and Meta-Analysis.
Synthesis in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Time Course of Hemostatic Disruptions After Traumatic Brain Injury: A Systematic Review of the Literature.Neurocritical care · 2021Pooled it
- The Risk of Deterioration in GCS13-15 Patients with Traumatic Brain Injury Identified by Computed Tomography Imaging: A Systematic Review and Meta-Analysis.Journal of neurotrauma · 2018Pooled it
- Risk factors for prognosis in patients with traumatic brain injury: A retrospective observational study.Medicine · 2026Observational
- Multi-dimensional plasma proteomic profiling elucidates molecular mechanisms and pathophysiological networks in pediatric severe traumatic brain injury.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026Article
- Improving severity grading of chemotherapy-induced myelosuppression in AML via data-driven and model-based deep learning.NPJ systems biology and applications · 2026Article
- Characterizing the impact of traumatic brain injury phenotype on coagulation dynamics in severely injured patients.Thrombosis research · 2026Article
- Article
- Evaluating the Efficacy of Longitudinal Coagulation Biomarkers to Predict in-Hospital Death in Comatose TBI Patients: A Time-Dependent Roc Curve Approach.Medical journal of the Islamic Republic of Iran · 2025Article
- Combined citicoline and Cerebrolysin for neuroprotection in traumatic brain injury: a retrospective cohort analysis.Frontiers in neurology · 2025Article
- Neuroprotective and neuroregenerative drugs after severe traumatic brain injury : A narrative review from a clinical perspective.Wiener klinische Wochenschrift · 2024Review
- EASIX is an effective marker in predicting mortality of traumatic brain injury patients.European journal of medical research · 2024Article
- Cancer Related Subarachnoid Hemorrhage: A Multicenter Retrospective Study Using Propensity Score Matching Analysis.Frontiers in cellular neuroscience · 2022Article
- Biofluid Biomarkers in Traumatic Brain Injury: A Systematic Scoping Review.Neurocritical care · 2021Article
- Acrolein Induces Systemic Coagulopathy via Autophagy-dependent Secretion of von Willebrand Factor in Mice after Traumatic Brain Injury.Neuroscience bulletin · 2021Article
- Genetic Variants Associated With Intraparenchymal Hemorrhage Progression After Traumatic Brain Injury.JAMA network open · 2021Article
- Coagulopathy and its effect on treatment and mortality in patients with traumatic intracranial hemorrhage.Acta neurochirurgica · 2021Article
- Ability of Fibrin Monomers to Predict Progressive Hemorrhagic Injury in Patients with Severe Traumatic Brain Injury.Neurocritical care · 2020Observational
- Bloodletting Puncture at Hand TwelveFrontiers in neuroscience · 2020Article
- Risk factors of acute coagulation dysfunction after aneurysmal subarachnoid hemorrhage.Chinese neurosurgical journal · 2018Article
- Therapeutic hypothermia in patients with coagulopathy following severe traumatic brain injury.Scandinavian journal of trauma, resuscitation and emergency medicine · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intracranial hemorrhage (ICH) after traumatic brain injury (TBI) commonly increases in size and coagulopathy has been implicated in such progression. Our aim is to perform a meta-analysis to assess their relationship. Cochrane library, PubMed, and EMBASE were searched for literatures. Pooled effect sizes and 95% confidential intervals (CIs) were calculated using random-effects model. We included six studies, involving 1700 participants with 540 progressive hemorrhagic injuries (PHIs). Our findings indicate that PT, D-dimer level, and INR value are positively associated with the risk of PHI. Higher level of PLT and Fg seemed to suggest a lower risk of PHI. Among these parameters, higher D-dimer level and INR value would possess more powerful strength in predicting PHI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.