ArticleJournal of the West African College of Surgeons
A COMPARATIVE STUDY OF INTRAMUSCULAR ACETAMINOPHEN VERSUS INTRAMUSCULAR PENTAZOCINE AS LABOUR ANALGESIA IN ZARIA, NORTHWESTERN NIGERIA.
Article in Journal of the West African College of Surgeons. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed, 1 citations in OpenAlex.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIntramuscular pentazocine is a common labour analgesic in Zaria, Nigeria due to its low cost and availability. Though also cheap and readily available the use of intramuscular acetaminophen is not popular and hence the need for a comparative study. AIM &
objectivesTo compare the efficacy of intramuscular acetaminophen versus intramuscular pentazocine on women in labour as well as the effects of both drugs on APGAR scores of their newborn. METHODOLOGY: A randomized, comparative study was conducted on 188 eligible, parturients from June to September, 2013. The subjects were selected during antenatal classes and early active labour, counseled, taught about the pain scoring systems after obtaining written consent from them. Randomization was done using the WINPEPI software by Abrahamson in order for each woman in labour to receive either intramuscular acetaminophen 15mg/kg stat or pentazocine 1mg/kg at cervical dilatation of 4-6cm. The data obtained included the patients demographics, hourly pain scores, APGAR scores, patients' satisfaction and side effects.
resultsThe mean age was 28.1years ± SD 5.2years. The majority of the subjects (53.5%) were Hausa-Fulani and 70.1% were muslims; 64% were booked for antenatal care while 58.5% had received secondary school education. The average duration of labour was 5.4hours. Acetaminophen was administered to 91(48%) subjects while pentazocine was administered to 97(52%). Sixty-nine percent and 80% experienced adequate pain relief in the acetaminophen and pentazocine groups respectively at one hour. The pain scores was statistically significant at one hour but comparable in both groups afterwards: p=0.01, 0.52, 0.338 and 0.389 at 1(st), 2(nd), 3(rd) and 4(th) hours on the linear/visual analogue scale and comparable on the verbal rating scale. There was no difference in the 1(st) and 5(th) minute APGAR scores of the babies delivered (p=0.24 and 0.63 respectively). Patients' satisfaction was comparable but the pentazocine group experienced more side effects.
conclusionIntramuscular acetaminophen gave comparable labour analgesia with fewer side effects when compared with pentazocine.
Indexed as
Identifiers
26457265PMC4553227W2414290887What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.