Evidence map›Paper›PMID 26457247›Full record

ArticleBioImpacts : BI2015

Bioimpacts of nanoparticle size: why it matters?

Jaleh Barar

Abstract read
In one paragraph

Article in BioImpacts : BI, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Preparation of Polymeric Nanoparticles for Gene Delivery.Methods in molecular biology (Clifton, N.J.) · 2027
    Article
  2. Review
  3. Article
  4. Article
  5. Green Synthesis of Metal Nanoparticles UsingNanotechnology, science and applications · 2025
    Review
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  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Jaleh BararResearch Center for Pharmaceutical Nanotechnology, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the last two decades, applications of nanotechnology are delivered to benefit the human society. The fact is that various nanomaterials are able to be tailor made to achieve desired properties. In biomedical field, nanotechnology has created great excitements to advance both diagnosis and therapy areas - the field so-called nanomedicines in different forms of nanoparticles (NPs) and nanosystems (NSs). It is noteworthy to mention NPs/NSs do not act similarly in the biological milieu, in which their biological behaviors/ impacts varies with size, morphology, and physicochemical characteristics. On the other hand, nanomedicines impacts on biological systems seem to be influenced by its possible interaction(s) with different bioelements of cell membrane, in particular the endocytic pathway(s) by which NPs/NSs can be internalized and localized. This latter phenomenon is influenced by membrane viscoelastic property, polymerization/depolymerization of cytoskeletal system, and the particle specification itself. Among all other properties of NPs/NSs, as shown by various researchers, the size is an important parameter in the fate of the particle. Accordingly, in-depth efforts to unravel the size dependent effects of nanomedicins can provide insights to design and develop more efficacious NSs with greater benefits and lower side effects. This editorial aims to highlight some important aspects of size dependent impacts NPs/NSs.

Indexed as

Drug deliveryDrug targetingInternalization pathwayNanBiotechnologyNanomedicines

Identifiers

PMID26457247
PMCPMC4597157

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.