Evidence map›Paper›PMID 26457181›Full record

ReviewExtreme physiology & medicine2015

The impact of extended bed rest on the musculoskeletal system in the critical care environment.

Selina M Parry, Zudin A Puthucheary

4 registry-linked trialsOpen access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Extreme physiology & medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 139 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
139citing papers in PubMed, 16 pooled it
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05055440 completednot on this mapstarted 2021, after this paper: background citation

Evaluation of Peripheral Muscle With Ultrassonografic of Critical Patients With Covid-19

TypeobservationalSponsorUniversity of PernambucoRan2021 to 2022Enrolled30ConditionsCOVID-19 Respiratory Infection
NCT05969145 nacompletednot on this mapstarted 2023, after this paper: background citation

The Effect of Hot-Cold Application to the Bladder After Orthopedic Surgery on Postoperative Urinary Retention

TypeinterventionalSponsorAnkara Yildirim Beyazıt UniversityRan2023 to 2024Enrolled60ConditionsPostoperative Urinary RetentionArmsapplication of thermophor
NCT06249789 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Enhancing Recovery in Hip Fracture Surgeries

TypeinterventionalSponsorHartford HospitalRan2024 to 2025Enrolled102ConditionsHip FracturesArmsSpinal Anesthesia, General Anesthesia
NCT06697470 recruitingnot on this mapstarted 2024, after this paper: background citation

Cross-sectional Study on the Variation of Muscle Thickness and Subcutaneous Tissues by Ultrasound and Bioelectrical Impedance in Association with the Fluid Balance of Patients in Intensive Care

Typeobservational_patient_registrySponsorDr F DuprezRan2024 to 2024Enrolled40ConditionsWeakness Acquired in the ICU, Muscle Wasting, Edema, Fluid OverloadArmsUltrasound and Bioelectrical Impedance Analysis for Muscle Thickness and Fluid Balance Assessment Translation
3 · Its place in the literature

Who cites it

139 citing papers in PubMed, 16 syntheses or guidelines pooled it, 359 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Complications after early versus late mobilization after an incidental durotomy: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Pooled it
  8. Pooled it
  9. Nonuniform loss of muscle strength and atrophy during bed rest: a systematic review.Journal of applied physiology (Bethesda, Md. : 1985) · 2021
    Pooled it
  10. Pooled it
  11. Pooled it
  12. ICU-acquired weakness.Intensive care medicine · 2020
    Pooled it
  13. Pooled it
  14. Pooled it
  15. Pooled it
  16. Pooled it
  17. Trial
  18. Trial
  19. Trial
  20. Trial

79 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 3 countries.

Selina M ParryDepartment of Physiotherapy, School of Health Sciences, The University of Melbourne, Level 7 Alan Gilbert Building, Parkville, Melbourne, VIC 3010 Australia.ORCID 0000-0003-2204-3143
Zudin A PuthuchearyDivision of Respiratory and Critical Care Medicine, National University Health System, Singapore, Singapore ; Institute of Health and Human Performance, University College London, London, UK.
National University Health System · SGThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prolonged immobility is harmful with rapid reductions in muscle mass, bone mineral density and impairment in other body systems evident within the first week of bed rest which is further exacerbated in individuals with critical illness. Our understanding of the aetiology and secondary consequences of prolonged immobilization in the critically ill is improving with recent and ongoing research to establish the cause, effect, and best treatment options. This review aims to describe the current literature on bed rest models for examining immobilization-induced changes in the musculoskeletal system and pathophysiology of immobilisation in critical illness including examination of intracellular signalling processes involved. Finally, the review examines the current barriers to early activity and mobilization and potential rehabilitation strategies, which are being, investigated which may reverse the effects of prolonged bed rest. Addressing the deleterious effects of immobilization is a major step in treatment and prevention of the public health issue, that is, critical illness survivorship.

Indexed as

Bed restCritical illnessIntensive care unit-acquired weaknessMuscle protein turnoverMuscle wastingRehabilitationSepsis

Identifiers

PMID26457181
PMCPMC4600281
OpenAlexW1958567138

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.