Evidence map›Paper›PMID 26456948›Full record

SynthesisHPB : the official journal of the International Hepato Pancreato Biliary Association2015

Calculating the risk of a pancreatic fistula after a pancreaticoduodenectomy: a systematic review.

Abigail E Vallance, Alastair L Young, Christian Macutkiewicz, Keith J Roberts, Andrew M Smith

Abstract readSystematic Review
In one paragraph

Synthesis in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Robotic Versus Laparoscopic Pancreaticoduodenectomy: A Review of Contemporary Evidence on Surgical Outcomes and Learning Curve.The international journal of medical robotics + computer assisted surgery : MRCAS · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. The Value of Blood T Cell Frequencies for Risk Prediction of Postoperative Complications in Pancreatic Cancer Surgery.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Perianastomotic Irrigation With Passive Drainage Dramatically Decreases POPF Rate After High-risk Pancreaticoduodenectomy.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Abigail E VallanceLeeds Teaching Hospitals NHS Trust, Leeds, UK.
Alastair L YoungLeeds Teaching Hospitals NHS Trust, Leeds, UK.
Christian MacutkiewiczLeeds Teaching Hospitals NHS Trust, Leeds, UK.
Keith J RobertsUniversity Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Andrew M SmithLeeds Teaching Hospitals NHS Trust, Leeds, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA post-operative pancreatic fistula (POPF) is a major cause of morbidity and mortality after a pancreaticoduodenectomy (PD). This systematic review aimed to identify all scoring systems to predict POPF after a PD, consider their clinical applicability and assess the study quality.

methodAn electronic search was performed of Medline (1946-2014) and EMBASE (1996-2014) databases. Results were screened according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, and quality assessed according to the QUIPS (quality in prognostic studies) tool.

resultsSix eligible scoring systems were identified. Five studies used the International Study Group on Pancreatic Fistula (ISGPF) definition. The proposed scores feature between two and five variables and of the 16 total variables, the majority (12) featured in only one score. Three scores could be fully completed pre-operatively whereas 1 score included intra-operative and two studies post-operative variables. Four scores were internally validated and of these, two scores have been subject to subsequent multicentre review. The median QUIPS score was 38 out of 50 (range 16-50).

conclusionThese scores show potential in calculating the individualized patient risk of POPF. There is, however, much variation in current scoring systems and further validation in large multicentre cohorts is now needed.

Indexed as

Pancreatic FistulaPostoperative ComplicationsGlobal HealthHumansIncidencePancreaticoduodenectomyPrognosisRisk AssessmentRisk Factors

Identifiers

PMID26456948
PMCPMC4605344

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.