Evidence map›Paper›PMID 26456544›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2016

Plasma Parathyroid Hormone Is Independently Related to Nocturnal Blood Pressure in Hypertensive Patients: The Styrian Hypertension Study.

Nicolas D Verheyen, Katharina Kienreich, Martin Gaksch, Adriana J van Ballegooijen, Martin R Grübler, Briain Ó Hartaigh, Johannes Schmid, Astrid Fahrleitner-Pammer, Elisabeth Kraigher-Krainer, Caterina Colantonio and 8 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 6 countries.

Nicolas D VerheyenDepartment of Cardiology, Medical University of Graz, Graz, Austria.
Katharina KienreichDepartment of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Graz, Austria.
Martin GakschDepartment of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Graz, Austria.
Adriana J van BallegooijenDepartment of Health Sciences and the EMGO+ Institute, VU University Amsterdam, Amsterdam, the Netherlands.
Martin R GrüblerDepartment of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Graz, Austria.
Briain Ó HartaighDepartment of Radiology, Dalio Institute of Cardiovascular Imaging, NewYork-Presbyterian Hospital and the Weill Cornell Medical College, New York, NY.
Johannes SchmidDepartment of Cardiology, Medical University of Graz, Graz, Austria.
Astrid Fahrleitner-PammerDepartment of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Graz, Austria.
Elisabeth Kraigher-KrainerMedizinische Klinik mit Schwerpunkt Kardiologie, Campus Virchow-Klinikum, Charité-Universitaetsmedizin Berlin, Berlin, Germany.
Caterina ColantonioDepartment of Cardiology, Medical University of Graz, Graz, Austria.
Evgeny BelyavskiyMedizinische Klinik mit Schwerpunkt Kardiologie, Campus Virchow-Klinikum, Charité-Universitaetsmedizin Berlin, Berlin, Germany.
Gerlies TreiberDepartment of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Graz, Austria.
Cristiana CatenaClinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.
Helmut BrusseeDepartment of Cardiology, Medical University of Graz, Graz, Austria.
Burkert PieskeDepartment of Cardiology, Medical University of Graz, Graz, Austria.
Winfried MärzHypertension Unit, Internal Medicine, Department of Experimental and Clinical Medical Sciences, University of Udine, Udine, Italy.
Andreas TomaschitzDepartment of Cardiology, Medical University of Graz, Graz, Austria.
Stefan PilzDepartment of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Graz, Austria.
Medical University of Graz · ATCharité - Universitätsmedizin Berlin · DEEMGO Institute for Health and Care Research · NLNewYork–Presbyterian Hospital · USUniversity of Udine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High parathyroid hormone (PTH) has been linked with high blood pressure (BP), but the relationship with 24-hour ambulatory blood pressure monitoring is largely unknown. The authors therefore analyzed cross-sectional data of 292 hypertensive patients participating in the Styrian Hypertension Study (mean age, 61±11 years; 53% women). Median plasma PTH (interquartile range) determined after an overnight fast was 49 pg/mL (39-61), mean daytime BP was 131/80±12/9 mm Hg, and mean nocturnal BP was 115/67±14/9 mm Hg. In multivariate regression analyses adjusted for BP and PTH-modifying parameters, PTH was significantly related to nocturnal systolic and diastolic BP (adjusted β-coefficient 0.140 [P=.03] and 0.175 [P<.01], respectively). PTH was not correlated with daytime BP readings. These data suggest a direct interrelationship between PTH and nocturnal BP regulation. Whether lowering high PTH concentrations reduces the burden of high nocturnal BP remains to be shown in future studies.

Indexed as

AgedBlood PressureBlood Pressure Monitoring, AmbulatoryCircadian RhythmCross-Sectional StudiesFemaleHumansHypertensionMaleMiddle AgedParathyroid HormoneRegression AnalysisRisk FactorsParathyroid Hormone

Identifiers

PMID26456544
PMCPMC8031576
OpenAlexW1899970769

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.