Evidence map›Paper›PMID 26454820›Full record

Observational studyThe international journal of cardiovascular imaging2016

Prognostic value of coronary CT angiography in diabetic patients: a 5-year follow up study.

Jonathan Nadjiri, Jörg Hausleiter, Simon Deseive, Albrecht Will, Eva Hendrich, Stefan Martinoff, Martin Hadamitzky

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in The international journal of cardiovascular imaging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Negative predictive value of stress myocardial perfusion imaging and coronary computed tomography angiography: A meta-analysis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Pooled it
  2. Pooled it
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Long-Term Prognostic Value of Coronary Computed Tomography Angiography.Current treatment options in cardiovascular medicine · 2017
    Review
  10. Cardiovascular imaging 2016 in the International Journal of Cardiovascular Imaging.The international journal of cardiovascular imaging · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jonathan NadjiriInstitut für Radiologie und Nuklearmedizin, Deutsches Herzzentrum München, Technische Universität München, Lazarettstrasse 36, 80636, Munich, Germany. j.nadjiri@gmx.net.
Jörg HausleiterMedizinische Klinik und Poliklinik I, Klinikum der Ludwig-Maximilians-Universität München, Munich, Germany.
Simon DeseiveMedizinische Klinik und Poliklinik I, Klinikum der Ludwig-Maximilians-Universität München, Munich, Germany.
Albrecht WillInstitut für Radiologie und Nuklearmedizin, Deutsches Herzzentrum München, Technische Universität München, Lazarettstrasse 36, 80636, Munich, Germany.
Eva HendrichInstitut für Radiologie und Nuklearmedizin, Deutsches Herzzentrum München, Technische Universität München, Lazarettstrasse 36, 80636, Munich, Germany.
Stefan MartinoffInstitut für Radiologie und Nuklearmedizin, Deutsches Herzzentrum München, Technische Universität München, Lazarettstrasse 36, 80636, Munich, Germany.
Martin HadamitzkyInstitut für Radiologie und Nuklearmedizin, Deutsches Herzzentrum München, Technische Universität München, Lazarettstrasse 36, 80636, Munich, Germany. mhy@dhm.mhn.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prevalence of coronary artery disease (CAD) is high in diabetic patients while diagnosis of early stage of CAD remains demanding. This study evaluates prognostic value of coronary computed tomography angiography (CCTA) for long-term outcome to predict cardiac events in oligosymptomatic diabetic patients. A cohort of 108 consecutive diabetic patients without angina pectoris or known CAD, undergoing CCTA was included. 1379 consecutive patients without diabetes were defined as a control group. Coronary artery calcium score (CACS), segment involvement score (SIS) and the segment stenosis score (SSS) were documented. The end point was a composite of cardiac events defined as all-cause death, nonfatal myocardial infarction, or unstable angina requiring hospitalization. Follow up period was 66.0 ± 14.2 month. 98% of initially enrolled patient were followed. During follow-up period 10 cardiac events within the diabetic cohort and 48 within the non-diabetic cohort were observed. Annual event rate in diabetic and non-diabetic patients was 1.74 and 0.64% respectively. In diabetic patients a multivariate analysis showed significant prognostic value over Framingham Score for SIS with a hazard ratio (HR) of 2.98 (95% CI 1.02, 8.72; p = 0.047) and SSS (HR 4.47, 95% CI 1.21, 16.49; p = 0.025), while CACS did not add prognostic value in this cohort. Annual event rate was 0% in diabetic patients with SIS = 0 and 3.9% in diabetic patients with SIS ≥ 8. CCTA allows for improved risk prediction for subsequent cardiac events in oligosymptomatic diabetic patients.

Indexed as

Multidetector Computed TomographyAgedAngina, UnstableCase-Control StudiesCoronary AngiographyCoronary Artery DiseaseCoronary StenosisDiabetic AngiopathiesDisease-Free SurvivalDisease ProgressionFemaleFollow-Up StudiesHospitalizationHumansKaplan-Meier EstimateMaleCoronary artery diseaseCoronary computed tomographic angiographyDiabetic patientsPlaque loadPrognostic value

Identifiers

PMID26454820

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.