Trial reportJournal of affective disorders2016
Randomized controlled trial to prevent postpartum depression in mothers on public assistance.
Trial report in Journal of affective disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- What Makes Parents of Young Children Stressed? A Systematic Review of Quantitative Studies.Clinical child and family psychology review · 2026Pooled it
- Interventions to Prevent Relapse or Recurrence of Preconception Anxiety and/or Depression in Perinatal Women: A Systematic Review.Maternal and child health journal · 2025Pooled it
- Proactive approaches to preventing postpartum depression in non-depressive pregnant women: a comprehensive scoping review.Frontiers in global women's health · 2025Pooled it
- Maternal Mental Health and Offspring Brain Development: An Umbrella Review of Prenatal Interventions.Biological psychiatry · 2023Pooled it
- Is collaborative care a key component for treating pregnant women with psychiatric symptoms (and additional psychosocial problems)? A systematic review.Archives of women's mental health · 2022Pooled it
- Universal prevention of distress aimed at pregnant women: a systematic review and meta-analysis of psychological interventions.BMC pregnancy and childbirth · 2021Pooled it
- Interpersonal Psychotherapy to Reduce Psychological Distress in Perinatal Women: A Systematic Review.International journal of environmental research and public health · 2020Pooled it
- Psychological interventions for depression and anxiety in pregnant Latina and Black women in the United States: A systematic review.Clinical psychology & psychotherapy · 2020Pooled it
- Collaborative tailoring of the Reach Out, Stay Strong Essentials (ROSE) program for pregnant veterans in the U.S. Veterans Health Administration: a qualitative case study of contextual conditions and adaptations.BMC health services research · 2025Trial
- Outcomes of the ROSE Sustainment (ROSES) Study, a sequential multiple assignment randomized implementation trial to determine the minimum necessary intervention to sustain a postpartum depression prevention program in agencies serving low-income pregnant people.Implementation science : IS · 2025Trial
- Practical resources for effective postpartum parenting (PREPP): a randomized controlled trial of a novel parent-infant dyadic intervention to reduce symptoms of postpartum depression.American journal of obstetrics & gynecology MFM · 2024Trial
- A randomised controlled trial evaluating the effect of a brief motivational intervention to promote breastfeeding in postpartum depression.Scientific reports · 2022Trial
- Protocol for the ROSE sustainment (ROSES) study, a sequential multiple assignment randomized trial to determine the minimum necessary intervention to maintain a postpartum depression prevention program in prenatal clinics serving low-income women.Implementation science : IS · 2018Trial
- An experimental test of the fetal programming hypothesis: Can we reduce child ontogenetic vulnerability to psychopathology by decreasing maternal depression?Development and psychopathology · 2018Trial
- Problem-Solving Education to Prevent Depression Among Low-Income Mothers: A Path Mediation Analysis in a Randomized Clinical Trial.JAMA network open · 2018Trial
- A Pilot Randomized Controlled Trial of a Computer-Delivered Brief Intervention for Substance Use and Risky Sex During Pregnancy.Journal of women's health (2002) · 2018Trial
- Feasibility, Acceptability, and Exploratory Efficacy of Implementing an Intervention for Preventing Postpartum Depression in Antepartum Hospitalized Patients With High-Risk Pregnancy Complications: A Mixed-Methods Experimental Study.Women's health issues : official publication of the Jacobs Institute of Women's HealthTrial
- Study protocol for a midwife-led psychoeducational intervention to reduce pregnancy-related anxiety in low-risk pregnant women.Frontiers in public health · 2026Article
- PROMATER: protocol for a randomized controlled trial of a digital self-guided intervention to promote perinatal mental health and reduce self-criticism.Frontiers in psychiatry · 2026Article
- Acceptability and efficacy of a smartphone application intervention for mental health care based on interpersonal psychotherapy for improving depression symptoms in prenatal women: Protocol for a randomized controlled trial.Internet interventions · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
introductionPostpartum depression (PPD) is a significant and common public health problem for women.
aimsTo examine the efficacy of an intervention based on the principles of interpersonal therapy (IPT) in reducing the risk of PPD in pregnant women.
methodsRandomized controlled trial of 205 pregnant women who were 18 years old or older, on public assistance, and at risk for PPD. Participants (mean age=23; 38% Hispanic and 23% Black) were randomized to either the IPT group intervention (n=104) or the treatment as usual control (TAU) program (n=101).
resultsAt 6 months, the overall depression rate in the intervention group (16%) was lower than the control group (31%) and the effect of the intervention was statistically significant at p<0.05. LIMITATIONS: It is unknown if findings will generalize to a more heterogeneous sample of women than the current study, such as women from a range of socio-economic and cultural backgrounds, or marital status. There was a differential amount of contact between TAU and intervention conditions.
conclusionsAn IPT based intervention during the prenatal period has the potential to reduce cases of PPD within 6 months postpartum in at risk mothers on public assistance.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.