ArticleGenome biology and evolution2015
Solving a Bloody Mess: B-Vitamin Independent Metabolic Convergence among Gammaproteobacterial Obligate Endosymbionts from Blood-Feeding Arthropods and the Leech Haementeria officinalis.
Article in Genome biology and evolution, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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39 citing papers in PubMed, 81 citations in OpenAlex.
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- Life history drives the assembly of the bacterial community associated with the Horn fly, Haematobia irritans L. (Diptera: Muscidae).Archives of microbiology · 2026Article
- Evolutionary Convergence of Nutritional Symbionts in Ticks.Environmental microbiology reports · 2025Article
- Unveiling detoxifying symbiosis and dietary influence on the Southern green shield bug microbiota.FEMS microbiology ecology · 2024Article
- Discovery of a novel symbiotic lineage associated with a hematophagous leech from the genusMicrobiology spectrum · 2024Article
- Endosymbioses Have Shaped the Evolution of Biological Diversity and Complexity Time and Time Again.Genome biology and evolution · 2024Review
- Comparative genomics of a novelMicrobial genomics · 2024Article
- Evolution of an Alternative Genetic Code in the Providencia Symbiont of the Hematophagous Leech Haementeria acuecueyetzin.Genome biology and evolution · 2023Article
- Microbiomes of Blood-Feeding Triatomines in the Context of Their Predatory Relatives and the Environment.Microbiology spectrum · 2023Article
- Changes in Bacterial Community Structure Across the Different Life Stages of Black Soldier Fly (Hermetia illucens).Microbial ecology · 2023Article
- Symbioses shape feeding niches and diversification across insects.Nature ecology & evolution · 2023Article
- Nuclear genetic diversity of head lice sheds light on human dispersal around the world.PloS one · 2023Article
- Convergent evolution of a labile nutritional symbiosis in ants.The ISME journal · 2022Article
- Phylogenetic relationship between the endosymbiont "Candidatus Riesia pediculicola" and its human louse host.Parasites & vectors · 2022Article
- Transitional genomes and nutritional role reversals identified for dual symbionts of adelgids (Aphidoidea: Adelgidae).The ISME journal · 2022Article
- Cryptic Genes for Interbacterial Antagonism DistinguishFrontiers in cellular and infection microbiology · 2022Article
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- When your host shuts down: larval diapause impacts host-microbiome interactions in Nasonia vitripennis.Microbiome · 2021Article
- The Origin and Evolution of Antistasin-like Proteins in Leeches (Hirudinida, Clitellata).Genome biology and evolution · 2021Article
- Mitogenome of the blood feeding leechMitochondrial DNA. Part B, Resources · 2020Article
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endosymbiosis is a common phenomenon in nature, especially between bacteria and insects, whose typically unbalanced diets are usually complemented by their obligate endosymbionts. While much interest and focus has been directed toward phloem-feeders like aphids and mealybugs, blood-feeders such as the Lone star tick (Amblyomma americanum), Glossina flies, and the human body louse (Pediculus humanus corporis) depend on obligate endosymbionts which complement their B-vitamin-deficient diets, and thus are required for growth and survival. Glossiphoniid leeches have also been found to harbor distinct endosymbionts housed in specialized organs. Here, we present the genome of the bacterial endosymbiont from Haementeria officinalis, first of a glossiphoniid leech. This as-yet-unnamed endosymbiont belongs to the Gammaproteobacteria, has a pleomorphic shape and is restricted to bacteriocytes. For this bacterial endosymbiont, we propose the name Candidatus Providencia siddallii. This symbiont possesses a highly reduced genome with high A+T content and a reduced set of metabolic capabilities, all of which are common characteristics of ancient obligate endosymbionts of arthropods. Its genome has retained many pathways related to the biosynthesis of B-vitamins, pointing toward a role in supplementing the blood-restricted diet of its host. Through comparative genomics against the endosymbionts of A. americanum, Glossina flies, and P. humanus corporis, we were able to detect a high degree of metabolic convergence among these four very distantly related endosymbiotic bacteria.
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