ArticleJournal of experimental botany2016
Overexpression of OsCYP19-4 increases tolerance to cold stress and enhances grain yield in rice (Oryza sativa).
Article in Journal of experimental botany, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Ectopic expression of a Penicillium oxalicum cyclophilin gene in Arabidopsis thaliana imparts tolerance to cold stress.Transgenic research · 2026Article
- TheGenes · 2025Article
- Comparative genomics and expression analysis of theFrontiers in plant science · 2025Article
- Genome-wide identification and expression analyses ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2024Article
- GWAS combined with linkage analysis reveals major QTLs and candidate genes of salt tolerance inFrontiers in plant science · 2024Article
- Rice plants treated with biochar derived from Spirulina (Frontiers in plant science · 2024Article
- Unlocking the Multifaceted Mechanisms of Bud Outgrowth: Advances in Understanding Shoot Branching.Plants (Basel, Switzerland) · 2023Review
- Article
- Insights into the genetic determination of tuber shape and eye depth in potato natural population based on autotetraploid potato genome.Frontiers in plant science · 2023Article
- Unearthing the Alleviatory Mechanisms of Brassinolide in Cold Stress in Rice.Life (Basel, Switzerland) · 2022Article
- Article
- Comparative Proteomics Reveals the Difference in Root Cold Resistance betweenPlants (Basel, Switzerland) · 2022Article
- Article
- Genomics and transcriptomics to protect rice (Frontiers in plant science · 2022Review
- The CyclophilinFrontiers in plant science · 2021Article
- iTRAQ protein profile analysis of sugar beet under salt stress: different coping mechanisms in leaves and roots.BMC plant biology · 2020Article
- Sequence characteristics of Medicago truncatula cyclophilin family members and function analysis of MsCYP20-3B involved in axillary shoot development.Molecular biology reports · 2020Article
- Golgi-localized cyclophilin 21 proteins negatively regulate ABA signalling via the peptidyl prolyl isomerase activity during early seedling development.Plant molecular biology · 2020Article
- DEAD-Box RNA Helicase 42 Plays a Critical Role in Pre-mRNA Splicing under Cold Stress.Plant physiology · 2020Article
- Plant Cyclophilins: Multifaceted Proteins With Versatile Roles.Frontiers in plant science · 2020Review
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Authors and funding
9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
AtCYP19-4 (also known as CYP5) was previously identified as interacting in vitro with GNOM, a member of a large family of ARF guanine nucleotide exchange factors that is required for proper polar localization of the auxin efflux carrier PIN1. The present study demonstrated that OsCYP19-4, a gene encoding a putative homologue of AtCYP19-4, was up-regulated by several stresses and showed over 10-fold up-regulation in response to cold. The study further demonstrated that the promoter of OsCYP19-4 was activated in response to cold stress. An OsCYP19-4-GFP fusion protein was targeted to the outside of the plasma membrane via the endoplasmic reticulum as determined using brefeldin A, a vesicle trafficking inhibitor. An in vitro assay with a synthetic substrate oligomer confirmed that OsCYP19-4 had peptidyl-prolyl cis-trans isomerase activity, as was previously reported for AtCYP19-4. Rice plants overexpressing OsCYP19-4 showed cold-resistance phenotypes with significantly increased tiller and spike numbers, and consequently enhanced grain weight, compared with wild-type plants. Based on these results, the authors suggest that OsCYP19-4 is required for developmental acclimation to environmental stresses, especially cold. Furthermore, the results point to the potential of manipulating OsCYP19-4 expression to enhance cold tolerance or to increase biomass.
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