ArticleAmerican journal of epidemiology2015
Vaccination and all-cause child mortality from 1985 to 2011: global evidence from the Demographic and Health Surveys.
Article in American journal of epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 3 syntheses or guidelines pooled it, 126 citations in OpenAlex.
- Herpes zoster vaccination and the risk of dementia: A systematic review and meta-analysis.Brain and behavior · 2024Pooled it
- Strengthening vaccination delivery system resilience in the context of protracted humanitarian crisis: a realist-informed systematic review.BMC health services research · 2022Pooled it
- Adult Vaccination as a Protective Factor for Dementia: A Meta-Analysis and Systematic Review of Population-Based Observational Studies.Frontiers in immunology · 2022Pooled it
- Observational
- Article
- Global health data precarity: Safeguarding the Demographic and Health Survey program as a global public good.Scientific data · 2025Article
- Construction of Development Scores to Analyze Inequalities in Childhood Immunization Coverage: A Global Analysis from 2000 to 2021.International journal of environmental research and public health · 2025Article
- Article
- Gender disparities in childhood vaccination in India: exploring the role of son preference using NFHS-5 data.Frontiers in public health · 2025Article
- Mortality rates in a cohort of infants attending immunization clinics in Uganda (2017-2019).PloS one · 2025Observational
- Health programme spillover effects on childhood vaccination in India: a difference-in-differences analysis of the Zinc and Oral Rehydration Salts Programme using retrospective demographic health surveys data.BMJ public health · 2025Article
- Incidence, healthcare-seeking behavior and barriers associated with seeking care for severe childhood pneumonia in rural Bangladesh: A prospective study.PLOS global public health · 2025Article
- Determinants of vaccination status among Somali children: evidence from a Countrywide cross-sectional survey.BMC pediatrics · 2024Article
- Are we really hesitant toward routine immunization: Findings from a cross-sectional study in urban area in the tribal dominant state of India.Journal of family medicine and primary care · 2024Article
- The effect of herpes zoster vaccination at different stages of the disease course of dementia: Two quasi-randomized studies.medRxiv : the preprint server for health sciences · 2024Article
- Inequality in Childhood Immunization Coverage: A Scoping Review of Data Sources, Analyses, and Reporting Methods.Vaccines · 2024Article
- Nonspecific Effects of the Bacillus Calmette-Guérin Vaccine in Portuguese Children Under 5 Years of Age: Protocol for a Population-Based Historical Birth Cohort Study.JMIR research protocols · 2024Article
- Health Expenditure, Institutional Quality, and Under-Five Mortality in Sub-Saharan African Countries.International journal of environmental research and public health · 2024Article
- Vaccination coverage, barriers and vaccine hesitancy in children up to 24 months old: a population survey in a state capital in the Western Amazon.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2024Article
- Psychological and Social Aspects of Vaccination Hesitancy-Implications for Travel Medicine in the Aftermath of the COVID-19 Crisis: A Narrative Review.Medicina (Kaunas, Lithuania) · 2023Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Based on models with calibrated parameters for infection, case fatality rates, and vaccine efficacy, basic childhood vaccinations have been estimated to be highly cost effective. We estimated the association of vaccination with mortality directly from survey data. Using 149 cross-sectional Demographic and Health Surveys, we determined the relationship between vaccination coverage and the probability of dying between birth and 5 years of age at the survey cluster level. Our data included approximately 1 million children in 68,490 clusters from 62 countries. We considered the childhood measles, bacillus Calmette-Guérin, diphtheria-pertussis-tetanus, polio, and maternal tetanus vaccinations. Using modified Poisson regression to estimate the relative risk of child mortality in each cluster, we also adjusted for selection bias that resulted from the vaccination status of dead children not being reported. Childhood vaccination, and in particular measles and tetanus vaccination, is associated with substantial reductions in childhood mortality. We estimated that children in clusters with complete vaccination coverage have a relative risk of mortality that is 0.73 (95% confidence interval: 0.68, 0.77) times that of children in a cluster with no vaccinations. Although widely used, basic vaccines still have coverage rates well below 100% in many countries, and our results emphasize the effectiveness of increasing coverage rates in order to reduce child mortality.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.