Evidence map›Paper›PMID 26453296›Full record

ReviewAndrology2016

Male hormonal contraception: looking back and moving forward.

M Y Roth, S T Page, W J Bremner

Registry-linked trialOpen access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Andrology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02754687 (Single Dose, Dose-Ranging Safety and Tolerability, Pharmacokinetics, and Pharmacodynamics Study of 11-β Methyl Nortestosterone Dodecylcarbonate), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02754687 phase1completednot on this map

Single Dose, Dose-Ranging Safety and Tolerability, Pharmacokinetics, and Pharmacodynamics Study of 11-β Methyl Nortestosterone Dodecylcarbonate (11β-MNTDC) in Healthy Men

TypeinterventionalSponsorPremier ResearchRan2016 to 2017Enrolled12ConditionsHealthy Men, Male ContraceptionArmsPlacebo, 11βmethyl nortestosterone dodecylcarbonate
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 34 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Review
  6. The future of male contraception: a fertile ground.Translational andrology and urology · 2018
    Review
  7. Article
  8. Male Hormonal Contraception: Where Are We Now?Current obstetrics and gynecology reports
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

M Y RothDepartment of Medicine and Center for Research in Reproduction and Contraception, University of Washington, Seattle, WA, USA.
S T PageDepartment of Medicine and Center for Research in Reproduction and Contraception, University of Washington, Seattle, WA, USA.
W J BremnerDepartment of Medicine and Center for Research in Reproduction and Contraception, University of Washington, Seattle, WA, USA.
University of Washington · US

Funding

Spermatogonial Stem Cell Self-Renewal and DifferentiationU54HD042454 · NICHD · UNIVERSITY OF WASHINGTON · PI BREMNER, WILLIAM J · 2002 to 2016
$26.9M
Intratesticular Sex Steroids and Spermatogenesis in ManK23HD073164 · NICHD · UNIVERSITY OF WASHINGTON · PI ROTH, MARA YVONNE · 2013 to 2015
$390k
NICHD NIH HHS K23 HD073164NICHD NIH HHS K23 HD073164-02NICHD NIH HHS U54 HD042454NICHD NIH HHS U54 HD-42454
6 · The paper itself

Abstract

Despite numerous contraceptive options available to women, approximately half of all pregnancies in the United States and worldwide are unplanned. Women and men support the development of reversible male contraception strategies, but none have been brought to market. Herein we review the physiologic basis for male hormonal contraception, the history of male hormonal contraception development, currents agents in development as well as the potential risks and benefits of male hormonal contraception for men.

Indexed as

ContraceptionContraceptive Agents, MaleHumansMaleNorprogesteronesTestosteroneTestosterone CongenersContraceptive Agents, MaleNorprogesteronesST 1435TestosteroneTestosterone Congenerscontraceptionspermatogenesistestosterone

Identifiers

PMID26453296
PMCPMC4718868
OpenAlexW1956585548

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.