ReviewCNS neuroscience & therapeutics2016
Motion Sickness: Current Knowledge and Recent Advance.
Review in CNS neuroscience & therapeutics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed, 1 synthesis or guideline pooled it, 204 citations in OpenAlex.
- Antihistamines for motion sickness.The Cochrane database of systematic reviews · 2022Pooled it
- An old approach to a novel problem: effect of combined balance therapy on virtual reality induced motion sickness: a randomized, placebo controlled, double-blinded study.BMC medical education · 2024Trial
- Evaluation of effects of optokinetic and rotational stimuli with functional head impulse test (fHIT) in individuals with motion sickness.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Trial
- Motorist's Disorientation Syndrome-A Narrative Review.Journal of functional morphology and kinesiology · 2026Review
- Assessment of antiemetic potential of schaftoside through modulation of dopaminergic, serotonergic and muscarinic signaling pathways: in vivo and in silico investigations.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Visual and vestibular reweighting after cyber- and space-sickness.Experimental physiology · 2026Article
- The gut feeling in motion sickness.Communications biology · 2025Review
- Preparation and evaluation of immediate and modified release tablets contained diphenidol hydrochloride.Scientific reports · 2025Article
- Functional and imaging anomalies of the vestibular system in motion sickness: a clinical observation study.BMC medical imaging · 2025Observational
- Effects of two kinds of vestibular function training on reducing motion sickness in college students.Frontiers in neurology · 2025Article
- A study on the mitigating effect of different music types on motion sickness based on EEG analysis.Frontiers in human neuroscience · 2025Article
- Investigating the impact of different road scenarios on the induction intensity of motion sickness in electric vehicle passengers.Frontiers in psychology · 2025Article
- Orexin-A and motion sickness: a systematic review of animal model studies.Frontiers in pharmacology · 2025Review
- Just 1-min exposure to a pure tone at 100 Hz with daily exposable sound pressure levels may improve motion sickness.Environmental health and preventive medicine · 2025Article
- Motion Syros: tradipitant effective in the treatment of motion sickness; a multicenter, randomized, double-blind, placebo-controlled study.Frontiers in neurology · 2025Article
- Review
- Effects of within-day intervals on adaptation to visually induced motion sickness in a virtual-reality motorcycling simulator.Scientific reports · 2024Article
- Electroencephalography microstate alterations reflect potential double-edged cognitive adaptation in Ménière's disease.CNS neuroscience & therapeutics · 2024Article
- Motion sickness resistant people showed suppressed steady-state visually evoked potential (SSVEP) under vection-inducing stimulation.Cognitive neurodynamics · 2024Article
- Incidence and Importance of Peripheral Vestibular Dysfunction in Adolescent Idiopathic Scoliosis.Children (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Motion sickness (MS) is a common physiological response to real or virtual motion. Numerous studies have investigated the neurobiological mechanism and the control measures of MS. This review summarizes the current knowledge about pathogenesis and pathophysiology, prediction, evaluation, and countermeasures of MS. The sensory conflict hypothesis is the most widely accepted theory for MS. Both the hippocampus and vestibular cortex might play a role in forming internal model. The pathophysiology focuses on the visceral afference, thermoregulation and MS-related neuroendocrine. Single-nucleotide polymorphisms (SNPs) in some genes and epigenetic modulation might contribute to MS susceptibility and habituation. Questionnaires, heart rate variability (HRV) and electrogastrogram (EGG) are useful for diagnosing and evaluating MS. We also list MS medications to guide clinical practice. Repeated real motion exposure and combined visual-vestibular interaction training accelerate the progress of habituation. Behavioral and dietary countermeasures, as well as physiotherapy, are also effective in alleviating MS symptoms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.