Evidence map›Paper›PMID 26452366›Full record

Trial reportBMC nephrology2015

The TALKS study to improve communication, logistical, and financial barriers to live donor kidney transplantation in African Americans: protocol of a randomized clinical trial.

Tara S Strigo, Patti L Ephraim, Iris Pounds, Felicia Hill-Briggs, Linda Darrell, Matthew Ellis, Debra Sudan, Hamid Rabb, Dorry Segev, Nae-Yuh Wang and 4 more

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC nephrology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02369354 nacompletednot on this map

Transplant Social Worker Support for Live Kidney Donation in African Americans

TypeinterventionalSponsorDuke UniversityRan2015 to 2019Enrolled300ConditionsKidney DiseaseArmsTALKS Social Worker Intervention, Financial Assistance Intervention
NCT06182475 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Increasing Equity in Live Donor Kidney Transplantation Through Effective Patient-Provider Communication

TypeinterventionalSponsorTemple UniversityRan2026 to 2027Enrolled70ConditionsKidney Disease, Chronic, End Stage Renal Disease, Kidney ReplacementArmsEPPComm Provider Training
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Interventions for increasing solid organ donor registration.The Cochrane database of systematic reviews · 2021
    Pooled it
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  5. Acceptability of a Mobile-Health Living Kidney Donor Advocacy Program for Black Wait-Listed Patients.International journal of environmental research and public health · 2021
    Trial
  6. Transplant social worker and donor financial assistance to increase living donor kidney transplants among African Americans: The TALKS Study, a randomized comparative effectiveness trial.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
    Trial
  7. Your Path to Transplant: A randomized controlled trial of a tailored expert system intervention to increase knowledge, attitudes, and pursuit of kidney transplant.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
    Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Tara S StrigoDivision of General Internal Medicine, Duke University School of Medicine, Durham, NC, 27701, USA. tara.strigo@duke.edu.
Patti L EphraimDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health and Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, MD, USA. pephraim@jhu.edu.
Iris PoundsDivision of General Internal Medicine, Duke University School of Medicine, Durham, NC, 27701, USA. iris.pounds@duke.edu.
Felicia Hill-BriggsWelch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Medical Institution and Division of General Internal Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA. fbriggs3@jhmi.edu.
Linda DarrellDepartment of Social Work, Morgan State University, Baltimore, MD, USA. linda.darrell@morgan.edu.
Matthew EllisDivision of Nephrology, Duke University School of Medicine, Durham, NC, USA. matthew.ellis@dm.duke.edu.
Debra SudanDivision of Transplantation, Duke University School of Medicine, Durham, NC, USA. debra.sudan@dm.duke.edu.
Hamid RabbDivision of Nephrology, Johns Hopkins School of Medicine, Baltimore, MD, USA. hrabb1@jhmi.edu.
Dorry SegevDivision of Transplantation, Johns Hopkins School of Medicine, Baltimore, MD, USA. dorry@jhmi.edu.
Nae-Yuh WangWelch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Medical Institution and Division of General Internal Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA. naeyuh@jhmi.edu.
Mary KaiserDivision of Transplantation, Johns Hopkins School of Medicine, Baltimore, MD, USA. mkaiser@jhmi.edu.
Margaret FalkovicDivision of General Internal Medicine, Duke University School of Medicine, Durham, NC, 27701, USA. margaret.falkovic@dm.duke.edu.
Jill F LebovDivision of General Internal Medicine, Duke University School of Medicine, Durham, NC, 27701, USA. jlebov@email.unc.edu.
L Ebony BoulwareDivision of General Internal Medicine, Duke University School of Medicine, Durham, NC, 27701, USA. ebony.boulware@duke.edu.
Duke University · USJohns Hopkins University · USJohns Hopkins Medicine · USMorgan State University · US

Funding

Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
Transplant Social Worker Support for Live Kidney Donation in African AmericansR01DK098759 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI BOULWARE, LEIGH E · 2012 to 2016
$1.5M
NCATS NIH HHS UL1 TR001079NIDDK NIH HHS 1R01DK098759NIDDK NIH HHS R01 DK098759
6 · The paper itself

Abstract

backgroundLive donor kidney transplantation (LDKT), an optimal therapy for many patients with end-stage kidney disease, is underutilized, particularly by African Americans. Potential recipient difficulties initiating and sustaining conversations about LDKT, identifying willing and medically eligible donors, and potential donors' logistical and financial hurdles have been cited as potential contributors to race disparities in LDKT. Few interventions specifically targeting these factors have been tested. METHODS/

designWe report the protocol of the Talking about Living Kidney Donation Support (TALKS) study, a study designed to evaluate the effectiveness of behavioral, educational and financial assistance interventions to improve access to LDKT among African Americans on the deceased donor kidney transplant recipient waiting list. We adapted a previously tested educational and social worker intervention shown to improve consideration and pursuit of LDKT among patients and their family members for its use among patients on the kidney transplant waiting list. We also developed a financial assistance intervention to help potential donors overcome logistical and financial challenges they might face during the pursuit of live kidney donation. We will evaluate the effectiveness of these interventions by conducting a randomized controlled trial in which patients on the deceased donor waiting list receive 1) usual care while on the transplant waiting list, 2) the educational and social worker intervention, or 3) the educational and social worker intervention plus the option of participating in the financial assistance program. The primary outcome of the randomized controlled trial will measure potential recipients' live kidney donor activation (a composite rate of live donor inquiries, completed new live donor evaluations, or live kidney donation) at 1 year. DISCUSSION: The TALKS study will rigorously assess the effectiveness of promising interventions to reduce race disparities in LDKT.

trial registrationNCT02369354.

Indexed as

Black or African AmericanKidney TransplantationAdolescentAdultAgedAged, 80 and overCommunication BarriersDonor SelectionFinancial SupportHealthcare DisparitiesHealth Knowledge, Attitudes, PracticeHumansLiving DonorsMiddle AgedPatient Education as TopicResearch Design

Identifiers

PMID26452366
PMCPMC4600221
OpenAlexW2158452403

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.