ArticleIEEE transactions on bio-medical engineering2016
Switched LPV Glucose Control in Type 1 Diabetes.
Article in IEEE transactions on bio-medical engineering, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 77 citations in OpenAlex.
- Artificial Pancreas: Clinical Study in Latin America Without Premeal Insulin Boluses.Journal of diabetes science and technology · 2018Trial
- Robust positive control of tumour growth using angiogenic inhibition.IET systems biology · 2023Article
- SPR-Based Sensor for the Early Detection or Monitoring of Kidney Problems.International journal of biomaterials · 2022Review
- Blood glucose concentration control for type 1 diabetic patients: a multiple-model strategy.IET systems biology · 2020Article
- ChatteringIET systems biology · 2020Article
- Artificial Pancreas: Evaluating the ARG Algorithm Without Meal Announcement.Journal of diabetes science and technology · 2019Article
- Adaptive Zone Model Predictive Control of Artificial Pancreas Based on Glucose- and Velocity-Dependent Control Penalties.IEEE transactions on bio-medical engineering · 2019Article
- Velocity-weighting & velocity-penalty MPC of an artificial pancreas: Improved safety & performance.Automatica : the journal of IFAC, the International Federation of Automatic Control · 2018Article
- Periodic zone-MPC with asymmetric costs for outpatient-ready safety of an artificial pancreas to treat type 1 diabetesAutomatica : the journal of IFAC, the International Federation of Automatic Control · 2016Article
- Reducing Glucose Variability Due to Meals and Postprandial Exercise in T1DM Using Switched LPV Control: In Silico Studies.Journal of diabetes science and technology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
Abstract
objectiveThe purpose of this paper is to regulate the blood glucose level in Type 1 Diabetes Mellitus patients with a practical and flexible procedure that can switch among a finite number of distinct controllers, depending on the user's choice.
methodsA switched linear parameter-varying controller with multiple switching regions, related to hypo-, hyper-, and euglycemia situations, is designed. The key feature is to arrange the controller into a framework that provides stability and performance guaranty.
resultsThe closed-loop performance is tested on the complete in silico adult cohort of the UVA/Padova metabolic simulator, which has been accepted by the U.S. Food and Drug Administration in lieu of animal trials. The outcome produces comparable or improved results with respect to previous works.
conclusionThe strategy is practical because it is based on a model tuned only with a priori patient information in order to cover the interpatient uncertainty. Results confirm that this control structure yields tangible improvements in minimizing risks of hyper- and hypoglycemia in scenarios with unannounced meals. SIGNIFICANCE: This flexible procedure opens the possibility of taking into account, at the design stage, unannounced meals and/or patients' physical exercise.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.