ArticleChemical communications (Cambridge, England)2015
Novel nonadride, heptadride and maleic acid metabolites from the byssochlamic acid producer Byssochlamys fulva IMI 40021 - an insight into the biosynthesis of maleidrides.
Article in Chemical communications (Cambridge, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Article
- Maleidride biosynthesis - construction of dimeric anhydrides - more than just heads or tails.Natural product reports · 2023Review
- Branching and converging pathways in fungal natural product biosynthesis.Fungal biology and biotechnology · 2022Review
- In silico analyses of maleidride biosynthetic gene clusters.Fungal biology and biotechnology · 2022Article
- Cytotoxicity and Nitric Oxide Production Inhibitory Activities of Compounds Isolated from the Plant Pathogenic FungusJournal of fungi (Basel, Switzerland) · 2021Article
- Article
- The sporothriolides. A new biosynthetic family of fungal secondary metabolites.Chemical science · 2020Article
- Uncovering biosynthetic relationships between antifungal nonadrides and octadrides.Chemical science · 2020Article
- Oxidative steps during the biosynthesis of squalestatin S1.Chemical science · 2019Article
- Characterisation of the biosynthetic pathway to agnestins A and B reveals the reductive route to chrysophanol in fungi.Chemical science · 2019Article
- Oryzines A & B, Maleidride Congeners fromJournal of fungi (Basel, Switzerland) · 2018Article
- Article
- Heterologous Production of Fungal Maleidrides Reveals the Cryptic Cyclization Involved in their Biosynthesis.Angewandte Chemie (International ed. in English) · 2016Article
- Metabolites from nematophagous fungi and nematicidal natural products from fungi as an alternative for biological control. Part I: metabolites from nematophagous ascomycetes.Applied microbiology and biotechnology · 2016Review
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9 authors.
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Abstract
The filamentous fungus Byssochlamys fulva strain IMI 40021 produces (+)-byssochlamic acid 1, its novel dihydroanalogue 2 and four related secondary metabolites. Agnestadrides A, 17 and B, 18 constitute a novel class of seven-membered ring, maleic anhydride-containing (hence termed heptadride) natural products. The putative maleic anhydride precursor 5 for both nonadride and heptadride biosynthesis was isolated as a fermentation product for the first time and its structure confirmed by synthesis. Acid 5 undergoes facile decarboxylation to anhydride 6. The generic term maleidrides is proposed to encompass biosynthetically-related compounds containing maleic anhydride moieties fused to an alicyclic ring, varying in size and substituents.
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