Evidence map›Paper›PMID 26451605›Full record

ReviewThe Journal of nutrition2015

Biomarkers of Nutrition for Development-Folate Review.

Lynn B Bailey, Patrick J Stover, Helene McNulty, Michael F Fenech, Jesse F Gregory, James L Mills, Christine M Pfeiffer, Zia Fazili, Mindy Zhang, Per M Ueland and 8 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The Journal of nutrition, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 289 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
289citing papers in PubMed, 12 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

289 citing papers in PubMed, 12 syntheses or guidelines pooled it.

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  19. A 2-Year Randomized Controlled Trial With Low-Dose B-Vitamin Supplementation Shows Benefits on Bone Mineral Density in Adults With Lower B12 Status.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Trial
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229 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Lynn B BaileyDepartment of Foods and Nutrition, University of Georgia, Athens, GA; raitend@mail.nih.gov folate@uga.edu.
Patrick J StoverDivision of Nutritional Sciences, Cornell University, Ithaca, NY;
Helene McNultyNorthern Ireland Centre for Food and Health, Biomedical Sciences Research Institute, University of Ulster, Londonderry, United Kingdom;
Michael F FenechGenome Health Nutrigenomics Laboratory, Food, Nutrition, and Bioproducts Flagship, Commonwealth Scientific and Industrial Research Organization, Adelaide, Australia;
Jesse F GregoryFood Science and Human Nutrition Department, University of Florida, Gainesville, FL;
James L MillsEunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD;
Christine M PfeifferNational Center for Environmental Health, CDC, Atlanta, GA;
Zia FaziliNational Center for Environmental Health, CDC, Atlanta, GA;
Mindy ZhangNational Center for Environmental Health, CDC, Atlanta, GA;
Per M UelandDepartment of Clinical Science, Univeristy of Bergen, Bergen, Norway;
Anne M MolloyInstitute of Molecular Medicine, Trinity College, Dublin, Ireland;
Marie A CaudillDivision of Nutritional Sciences, Cornell University, Ithaca, NY;
Barry ShaneDepartment of Nutritional Sciences and Toxicology, University of California-Berkeley, Berkeley, CA;
Robert J BerryNational Center on Birth Defects and Developmental Disabilities, CDC, Atlanta, GA; and.
Regan L BaileyOffice of Dietary Supplements, NIH, Bethesda, MD.
Dorothy B HausmanDepartment of Foods and Nutrition, University of Georgia, Athens, GA;
Ramkripa RaghavanEunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD;
Daniel J RaitenEunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD; raitend@mail.nih.gov folate@uga.edu.

Funding

Genetic Factors in Birth DefectsZIAHD008792 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI MILLS, JAMES · 2009 to 2023
$5.0M
NICHD Health Research Board Of Ireland Neural Tube Defects StudyZIAHD002502 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI MILLS, JAMES · 2009 to 2022
$2.9M
6 · The paper itself

Abstract

The Biomarkers of Nutrition for Development (BOND) project is designed to provide evidence-based advice to anyone with an interest in the role of nutrition in health. Specifically, the BOND program provides state-of-the-art information and service with regard to selection, use, and interpretation of biomarkers of nutrient exposure, status, function, and effect. To accomplish this objective, expert panels are recruited to evaluate the literature and to draft comprehensive reports on the current state of the art with regard to specific nutrient biology and available biomarkers for assessing nutrients in body tissues at the individual and population level. Phase I of the BOND project includes the evaluation of biomarkers for 6 nutrients: iodine, iron, zinc, folate, vitamin A, and vitamin B-12. This review represents the second in the series of reviews and covers all relevant aspects of folate biology and biomarkers. The article is organized to provide the reader with a full appreciation of folate's history as a public health issue, its biology, and an overview of available biomarkers (serum folate, RBC folate, and plasma homocysteine concentrations) and their interpretation across a range of clinical and population-based uses. The article also includes a list of priority research needs for advancing the area of folate biomarkers related to nutritional health status and development.

Indexed as

BiomarkersDietary SupplementsFolic AcidHumansIodineIronNutritional StatusNutrition AssessmentRecommended Dietary AllowancesVitamin AVitamin B 12ZincBiomarkersFolic AcidIodineIronVitamin AVitamin B 12ZincBONDfolate biomarkershomocysteineRBC folateserum folate

Identifiers

PMID26451605
PMCPMC4478945

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.