ReviewBioMed research international2015
Rare Diseases Leading to Childhood Glaucoma: Epidemiology, Pathophysiogenesis, and Management.
Review in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Micropulse Cyclophotocoagulation Versus Continuous Wave Cyclophotocoagulation: A Meta-Analysis.Journal of glaucoma · 2026Pooled it
- Pooled it
- Pathophysiology, diagnosis, and management of glaucoma associated with Sturge-Weber syndrome.International ophthalmology · 2018Pooled it
- Diffuse Choroidal Hemangioma in Sturge-Weber Syndrome: Correlation between Clinical Features, Imaging, and Treatment Response.Ocular oncology and pathology · 2026Article
- The first report of primary hypotonia with abnormal electromyogram and CBS mutation in a Chinese child.BMC medical genomics · 2026Article
- Optic disc morphology in congenital glaucoma.Eye (London, England) · 2025Article
- Prevalence of glaucoma and characteristics of ocular manifestations in patients with Naevus of Ota.BMJ open ophthalmology · 2025Article
- Pathogenic variants identification in primary congenital glaucoma patients using whole exome sequencing.Scientific reports · 2025Article
- Exploring Glaucoma: From Pathogenesis to Emerging Diagnostic and Management Strategies.Journal of ophthalmology · 2025Review
- A Case of Congenital Glaucoma in a 5-Year-Old Patient With Sturge-Weber Syndrome and Oculodermal Melanocytosis.Case reports in ophthalmological medicine · 2025Article
- Glaucoma and Systemic Disease.Life (Basel, Switzerland) · 2023Review
- An update on ophthalmological perspectives in oculodermal melanocytosis (Nevus of Ota).Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Review
- Congenital ciliary body cysts causing lens abnormalities and secondary angle closure glaucoma in a child.American journal of ophthalmology case reports · 2022Article
- The genetics of glaucoma: Disease associations, personalised risk assessment and therapeutic opportunities-A review.Clinical & experimental ophthalmology · 2022Review
- Bilateral Phakomatosis Cesiomarmorata With Ocular Melanocytosis and Secondary Glaucoma.Cureus · 2022Article
- Novel compound heterozygous mutations inMolecular medicine reports · 2021Article
- Progressive retinal vessel malformation in a premature infant with Sturge-Weber syndrome: a case report and a literature review of ocular manifestations in Sturge-Weber syndrome.BMC ophthalmology · 2021Article
- Characteristics and long-term outcomes of childhood glaucoma: a retrospective-cohort study.F1000Research · 2021Article
- Near-Infrared Reflectance Imaging in Retinal Diseases Affecting Young Patients.Journal of ophthalmology · 2021Review
- Incidence of Sturge-Weber syndrome and associated ocular involvement in Olmsted County, Minnesota, United States.Ophthalmic genetics · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Noteworthy heterogeneity exists in the rare diseases associated with childhood glaucoma. Primary congenital glaucoma is mostly sporadic; however, 10% to 40% of cases are familial. CYP1B1 gene mutations seem to account for 87% of familial cases and 27% of sporadic cases. Childhood glaucoma is classified in primary and secondary congenital glaucoma, further divided as glaucoma arising in dysgenesis associated with neural crest anomalies, phakomatoses, metabolic disorders, mitotic diseases, congenital disorders, and acquired conditions. Neural crest alterations lead to the wide spectrum of iridocorneal trabeculodysgenesis. Systemic diseases associated with childhood glaucoma include the heterogenous group of phakomatoses where glaucoma is frequently encountered in the Sturge-Weber syndrome and its variants, in phakomatosis pigmentovascularis associated with oculodermal melanocytosis, and more rarely in neurofibromatosis type 1. Childhood glaucoma is also described in systemic disorders of mitotic and metabolic activity. Acquired secondary glaucoma has been associated with uveitis, trauma, drugs, and neoplastic diseases. A database research revealed reports of childhood glaucoma in rare diseases, which do not include glaucoma in their manifestation. These are otopalatodigital syndrome, complete androgen insensitivity, pseudotrisomy 13, Brachmann-de Lange syndrome, acrofrontofacionasal dysostosis, caudal regression syndrome, and Wolf-Hirschhorn syndrome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.