Evidence map›Paper›PMID 26451279›Full record

ReviewAdipocyte

Adipogenesis is under surveillance of Hsp90 and the high molecular weight Immunophilin FKBP51.

Judith Toneatto, Nancy L Charó, Natalia M Galigniana, Graciela Piwien-Pilipuk

Open access · goldAbstract readReview
In one paragraph

Review in Adipocyte. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Judith ToneattoLaboratory of Nuclear Architecture; Instituto de Biología y Medicina Experimental - CONICET ; Buenos Aires, Argentina.
Nancy L CharóLaboratory of Nuclear Architecture; Instituto de Biología y Medicina Experimental - CONICET ; Buenos Aires, Argentina.
Natalia M GalignianaLaboratory of Nuclear Architecture; Instituto de Biología y Medicina Experimental - CONICET ; Buenos Aires, Argentina.
Graciela Piwien-PilipukLaboratory of Nuclear Architecture; Instituto de Biología y Medicina Experimental - CONICET ; Buenos Aires, Argentina.
Consejo Nacional de Investigaciones Científicas y Técnicas · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adipose tissue plays a central role in the control of energy balance as well as in the maintenance of metabolic homeostasis. It was not until recently that the first evidences of the role of heat shock protein (Hsp) 90 and high molecular weight immunophilin FKBP51 have been described in the process of adipocyte differentiation. Recent reports describe their role in the regulation of PPARγ, a key transcription factor in the control of adipogenesis and the maintenance of the adipocyte phenotype. In addition, novel roles have been uncovered for FKBP51 in the organization of the architecture of the nucleus through its participation in the reorganization of the nuclear lamina. Therefore, the aim of this review is to integrate and discuss the recent advances in the field, with special emphasis on the roles of Hsp90 and FKBP51 in the process of adipocyte differentiation.

Indexed as

adipogenesisFKBP51Hsp90nuclear laminaPPARγ

Identifiers

PMID26451279
PMCPMC4573184
OpenAlexW1555364331

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.