Evidence map›Paper›PMID 26451132›Full record

ArticleClinical and molecular allergy : CMA2015

AIT (allergen immunotherapy): a model for the "precision medicine".

Giovanni Passalacqua, Giorgio Walter Canonica

Abstract read
In one paragraph

Article in Clinical and molecular allergy : CMA, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Bridging Rare to Common Diseases: Precision Medicine and the Transforming Landscape of Pediatric Allergy and Immunology.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. A WAO - ARIA - GAThe World Allergy Organization journal · 2020
    Article
  7. Review
  8. Long-Term Therapy with Corticosteroids in Nasal Polyposis: A Bone Metabolism Assessment.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2019
    Article
  9. Article
  10. Article
  11. Personalized Medicine in Allergy.Allergy, asthma & immunology research · 2017
    Review
  12. Benefit of SLIT and SCIT for Allergic Rhinitis and Asthma.Current allergy and asthma reports · 2016
    Review
  13. Therapeutic interventions in severe asthma.The World Allergy Organization journal · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Giovanni PassalacquaAllergy and Respiratory Diseases, Department of Internal Medicine, S. Martino Hospital, IRCCS San Martino-IST-University of Genoa, Pad.Maragliano, L.go R Benzi 10, 16133 Genoa, Italy.
Giorgio Walter CanonicaAllergy and Respiratory Diseases, Department of Internal Medicine, S. Martino Hospital, IRCCS San Martino-IST-University of Genoa, Pad.Maragliano, L.go R Benzi 10, 16133 Genoa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The interpretation of medical approaches, especially therapy, evolved rapidly in the last century. Starting from the simple description of symptoms, we moved to the pathophysiological descriptions, to the evidence-based medicine, until the so-called "precision medicine". This latter can be defined as a structural model aimed at customizing healthcare, with medical decisions/products tailored on an individual patient at a highly detailed level. In this sense, allergen immunotherapy represents an optimal model of "precision medicine", since we know and describe symptoms, function, aetiological agents at molecular level, and we have the possibility to intervene on the natural history of the disease. If considered under the point of view of pharmaco-economy, that is prescribing the optimal treatment to the right patient, allergen immunotherapy represents an almost-ideal model of precision medicine.

Indexed as

Allergen immunotherapyPersonalized medicinePrecision medicine

Identifiers

PMID26451132
PMCPMC4597399

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.