ArticleDatabase : the journal of biological databases and curation2015
ProPepper: a curated database for identification and analysis of peptide and immune-responsive epitope composition of cereal grain protein families.
Article in Database : the journal of biological databases and curation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 43 citations in OpenAlex.
- Peptide Utility (PU) search server: A new tool for peptide sequence search from multiple databases.Heliyon · 2022Article
- Tritordeum as an Innovative Alternative to Wheat: A Comparative Digestion Study on Bread.Molecules (Basel, Switzerland) · 2022Article
- Development of a Sequence Searchable Database of Celiac Disease-Associated Peptides and Proteins for Risk Assessment of Novel Food Proteins.Frontiers in allergy · 2022Article
- Article
- Perennial Ryegrass Contains Gluten-Like Proteins That Could Contaminate Cereal Crops.Frontiers in nutrition · 2021Article
- Comprehensive Comparison of Clinically Relevant Grain Proteins in Modern and Traditional Bread Wheat Cultivars.International journal of molecular sciences · 2020Article
- Mapping Coeliac Toxic Motifs in the Prolamin Seed Storage Proteins of Barley, Rye, and Oats Using a Curated Sequence Database.Frontiers in nutrition · 2020Article
- BIOPEP-UWM Database of Bioactive Peptides: Current Opportunities.International journal of molecular sciences · 2019Article
- Modern Approaches in the Identification and Quantification of Immunogenic Peptides in Cereals by LC-MS/MS.Frontiers in plant science · 2019Review
- Genome mapping of seed-borne allergens and immunoresponsive proteins in wheat.Science advances · 2018Article
- A curated gluten protein sequence database to support development of proteomics methods for determination of gluten in gluten-free foods.Journal of proteomics · 2017Article
- Characterization of globulin storage proteins of a low prolamin cereal species in relation to celiac disease.Scientific reports · 2017Article
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ProPepper is a database that contains prolamin proteins identified from true grasses (Poaceae), their peptides obtained with single- and multi-enzyme in silico digestions as well as linear T- and B-cell-specific epitopes that are responsible for wheat-related food disorders. The integrated database and analysis platform contains datasets that are collected from multiple public databases (UniprotKB, IEDB, NCBI GenBank), manually curated and annotated, and interpreted in three main data tables: Protein-, Peptide- and Epitope list views that are cross-connected by unique identifications. Altogether 21 genera and 80 different species are represented. Currently, the database contains 2146 unique and complete protein sequences related to 2618 GenBank entries and 35 657 unique peptide sequences that are a result of 575 110 unique digestion events obtained by in silico digestion methods involving six proteolytic enzymes and their combinations. The interface allows advanced global and parametric search functions along with a download option, with direct connections to the relevant public databases. Database URL: https://propepper.net.
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