Evidence map›Paper›PMID 26450706›Full record

ArticlePlant physiology2015

Developmental and Metabolic Plasticity of White-Skinned Grape Berries in Response to Botrytis cinerea during Noble Rot.

Barbara Blanco-Ulate, Katherine C H Amrine, Thomas S Collins, Rosa M Rivero, Ariel R Vicente, Abraham Morales-Cruz, Carolyn L Doyle, Zirou Ye, Greg Allen, Hildegarde Heymann and 2 more

Abstract read
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In one paragraph

Article in Plant physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed.

  1. Review
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  10. Review
  11. Frontiers in plant science · 2024
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  14. Review
  15. The use of a candidate gene approach to studyFrontiers in plant science · 2023
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  17. Metatranscriptomic Analyses Reveal the Functional Role ofJournal of fungi (Basel, Switzerland) · 2022
    Article
  18. Article
  19. Antifungal mechanism of (Frontiers in microbiology · 2022
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Barbara Blanco-UlateDepartment of Viticulture and Enology, University of California, Davis, California 95616 (B.B.-U., K.C.H.A., T.S.C., A.M.-C., C.L.D., Z.Y., H.H., S.E.E., D.C.);Viticulture and Enology Program, Washington State University, Tri-Cities, Richland, Washington 99354 (T.S.C.);Centro de Edafología y Biología Aplicada del Segura-Consejo Superior de Investigaciones Científicas, 30100 Murcia, Spain (R.M.R.);Consejo Nacional de Investigaciones Científicas y Técnicas, 1900 La Plata, Argentina (A.R.V.);Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de La Plata, 1900 La Plata, Argentina (A.R.V.); andDolce Winery, Oakville, California 94562 (G.A.).ORCID http://orcid.org/0000-0002-8819-9207
Katherine C H AmrineDepartment of Viticulture and Enology, University of California, Davis, California 95616 (B.B.-U., K.C.H.A., T.S.C., A.M.-C., C.L.D., Z.Y., H.H., S.E.E., D.C.);Viticulture and Enology Program, Washington State University, Tri-Cities, Richland, Washington 99354 (T.S.C.);Centro de Edafología y Biología Aplicada del Segura-Consejo Superior de Investigaciones Científicas, 30100 Murcia, Spain (R.M.R.);Consejo Nacional de Investigaciones Científicas y Técnicas, 1900 La Plata, Argentina (A.R.V.);Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de La Plata, 1900 La Plata, Argentina (A.R.V.); andDolce Winery, Oakville, California 94562 (G.A.).ORCID http://orcid.org/0000-0001-7089-8029
Thomas S CollinsDepartment of Viticulture and Enology, University of California, Davis, California 95616 (B.B.-U., K.C.H.A., T.S.C., A.M.-C., C.L.D., Z.Y., H.H., S.E.E., D.C.);Viticulture and Enology Program, Washington State University, Tri-Cities, Richland, Washington 99354 (T.S.C.);Centro de Edafología y Biología Aplicada del Segura-Consejo Superior de Investigaciones Científicas, 30100 Murcia, Spain (R.M.R.);Consejo Nacional de Investigaciones Científicas y Técnicas, 1900 La Plata, Argentina (A.R.V.);Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de La Plata, 1900 La Plata, Argentina (A.R.V.); andDolce Winery, Oakville, California 94562 (G.A.).
Rosa M RiveroDepartment of Viticulture and Enology, University of California, Davis, California 95616 (B.B.-U., K.C.H.A., T.S.C., A.M.-C., C.L.D., Z.Y., H.H., S.E.E., D.C.);Viticulture and Enology Program, Washington State University, Tri-Cities, Richland, Washington 99354 (T.S.C.);Centro de Edafología y Biología Aplicada del Segura-Consejo Superior de Investigaciones Científicas, 30100 Murcia, Spain (R.M.R.);Consejo Nacional de Investigaciones Científicas y Técnicas, 1900 La Plata, Argentina (A.R.V.);Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de La Plata, 1900 La Plata, Argentina (A.R.V.); andDolce Winery, Oakville, California 94562 (G.A.).ORCID http://orcid.org/0000-0003-3880-0241
Ariel R VicenteDepartment of Viticulture and Enology, University of California, Davis, California 95616 (B.B.-U., K.C.H.A., T.S.C., A.M.-C., C.L.D., Z.Y., H.H., S.E.E., D.C.);Viticulture and Enology Program, Washington State University, Tri-Cities, Richland, Washington 99354 (T.S.C.);Centro de Edafología y Biología Aplicada del Segura-Consejo Superior de Investigaciones Científicas, 30100 Murcia, Spain (R.M.R.);Consejo Nacional de Investigaciones Científicas y Técnicas, 1900 La Plata, Argentina (A.R.V.);Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de La Plata, 1900 La Plata, Argentina (A.R.V.); andDolce Winery, Oakville, California 94562 (G.A.).
Abraham Morales-CruzDepartment of Viticulture and Enology, University of California, Davis, California 95616 (B.B.-U., K.C.H.A., T.S.C., A.M.-C., C.L.D., Z.Y., H.H., S.E.E., D.C.);Viticulture and Enology Program, Washington State University, Tri-Cities, Richland, Washington 99354 (T.S.C.);Centro de Edafología y Biología Aplicada del Segura-Consejo Superior de Investigaciones Científicas, 30100 Murcia, Spain (R.M.R.);Consejo Nacional de Investigaciones Científicas y Técnicas, 1900 La Plata, Argentina (A.R.V.);Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de La Plata, 1900 La Plata, Argentina (A.R.V.); andDolce Winery, Oakville, California 94562 (G.A.).ORCID http://orcid.org/0000-0002-6122-2649
Carolyn L DoyleDepartment of Viticulture and Enology, University of California, Davis, California 95616 (B.B.-U., K.C.H.A., T.S.C., A.M.-C., C.L.D., Z.Y., H.H., S.E.E., D.C.);Viticulture and Enology Program, Washington State University, Tri-Cities, Richland, Washington 99354 (T.S.C.);Centro de Edafología y Biología Aplicada del Segura-Consejo Superior de Investigaciones Científicas, 30100 Murcia, Spain (R.M.R.);Consejo Nacional de Investigaciones Científicas y Técnicas, 1900 La Plata, Argentina (A.R.V.);Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de La Plata, 1900 La Plata, Argentina (A.R.V.); andDolce Winery, Oakville, California 94562 (G.A.).
Zirou YeDepartment of Viticulture and Enology, University of California, Davis, California 95616 (B.B.-U., K.C.H.A., T.S.C., A.M.-C., C.L.D., Z.Y., H.H., S.E.E., D.C.);Viticulture and Enology Program, Washington State University, Tri-Cities, Richland, Washington 99354 (T.S.C.);Centro de Edafología y Biología Aplicada del Segura-Consejo Superior de Investigaciones Científicas, 30100 Murcia, Spain (R.M.R.);Consejo Nacional de Investigaciones Científicas y Técnicas, 1900 La Plata, Argentina (A.R.V.);Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de La Plata, 1900 La Plata, Argentina (A.R.V.); andDolce Winery, Oakville, California 94562 (G.A.).
Greg AllenDepartment of Viticulture and Enology, University of California, Davis, California 95616 (B.B.-U., K.C.H.A., T.S.C., A.M.-C., C.L.D., Z.Y., H.H., S.E.E., D.C.);Viticulture and Enology Program, Washington State University, Tri-Cities, Richland, Washington 99354 (T.S.C.);Centro de Edafología y Biología Aplicada del Segura-Consejo Superior de Investigaciones Científicas, 30100 Murcia, Spain (R.M.R.);Consejo Nacional de Investigaciones Científicas y Técnicas, 1900 La Plata, Argentina (A.R.V.);Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de La Plata, 1900 La Plata, Argentina (A.R.V.); andDolce Winery, Oakville, California 94562 (G.A.).
Hildegarde HeymannDepartment of Viticulture and Enology, University of California, Davis, California 95616 (B.B.-U., K.C.H.A., T.S.C., A.M.-C., C.L.D., Z.Y., H.H., S.E.E., D.C.);Viticulture and Enology Program, Washington State University, Tri-Cities, Richland, Washington 99354 (T.S.C.);Centro de Edafología y Biología Aplicada del Segura-Consejo Superior de Investigaciones Científicas, 30100 Murcia, Spain (R.M.R.);Consejo Nacional de Investigaciones Científicas y Técnicas, 1900 La Plata, Argentina (A.R.V.);Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de La Plata, 1900 La Plata, Argentina (A.R.V.); andDolce Winery, Oakville, California 94562 (G.A.).
Susan E EbelerDepartment of Viticulture and Enology, University of California, Davis, California 95616 (B.B.-U., K.C.H.A., T.S.C., A.M.-C., C.L.D., Z.Y., H.H., S.E.E., D.C.);Viticulture and Enology Program, Washington State University, Tri-Cities, Richland, Washington 99354 (T.S.C.);Centro de Edafología y Biología Aplicada del Segura-Consejo Superior de Investigaciones Científicas, 30100 Murcia, Spain (R.M.R.);Consejo Nacional de Investigaciones Científicas y Técnicas, 1900 La Plata, Argentina (A.R.V.);Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de La Plata, 1900 La Plata, Argentina (A.R.V.); andDolce Winery, Oakville, California 94562 (G.A.).ORCID http://orcid.org/0000-0002-8394-6736
Dario CantuDepartment of Viticulture and Enology, University of California, Davis, California 95616 (B.B.-U., K.C.H.A., T.S.C., A.M.-C., C.L.D., Z.Y., H.H., S.E.E., D.C.);Viticulture and Enology Program, Washington State University, Tri-Cities, Richland, Washington 99354 (T.S.C.);Centro de Edafología y Biología Aplicada del Segura-Consejo Superior de Investigaciones Científicas, 30100 Murcia, Spain (R.M.R.);Consejo Nacional de Investigaciones Científicas y Técnicas, 1900 La Plata, Argentina (A.R.V.);Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de La Plata, 1900 La Plata, Argentina (A.R.V.); andDolce Winery, Oakville, California 94562 (G.A.) dacantu@ucdavis.edu.ORCID http://orcid.org/0000-0002-4858-1508

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Noble rot results from exceptional infections of ripe grape (Vitis vinifera) berries by Botrytis cinerea. Unlike bunch rot, noble rot promotes favorable changes in grape berries and the accumulation of secondary metabolites that enhance wine grape composition. Noble rot-infected berries of cv Sémillon, a white-skinned variety, were collected over 3 years from a commercial vineyard at the same time that fruit were harvested for botrytized wine production. Using an integrated transcriptomics and metabolomics approach, we demonstrate that noble rot alters the metabolism of cv Sémillon berries by inducing biotic and abiotic stress responses as well as ripening processes. During noble rot, B. cinerea induced the expression of key regulators of ripening-associated pathways, some of which are distinctive to the normal ripening of red-skinned cultivars. Enhancement of phenylpropanoid metabolism, characterized by a restricted flux in white-skinned berries, was a common outcome of noble rot and red-skinned berry ripening. Transcript and metabolite analyses together with enzymatic assays determined that the biosynthesis of anthocyanins is a consistent hallmark of noble rot in cv Sémillon berries. The biosynthesis of terpenes and fatty acid aroma precursors also increased during noble rot. We finally characterized the impact of noble rot in botrytized wines. Altogether, the results of this work demonstrated that noble rot causes a major reprogramming of berry development and metabolism. This desirable interaction between a fruit and a fungus stimulates pathways otherwise inactive in white-skinned berries, leading to a greater accumulation of compounds involved in the unique flavor and aroma of botrytized wines.

Indexed as

Gene Expression Regulation, PlantAnthocyaninsBotrytisFruitGene Expression ProfilingGene Expression Regulation, DevelopmentalHost-Pathogen InteractionsMetabolomicsPlant DiseasesVitisWineAnthocyanins

Identifiers

PMID26450706
PMCPMC4677888

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