Evidence map›Paper›PMID 26450697›Full record

ArticleAdvanced healthcare materials2015

Carbohydrate-Conjugated Hollow Oblate Mesoporous Silica Nanoparticles as Nanoantibiotics to Target Mycobacteria.

Nanjing Hao, Xuan Chen, Seaho Jeon, Mingdi Yan

Abstract read
In one paragraph

Article in Advanced healthcare materials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Photothermal-Immunomodulatory Hydrogel Reinforced by TiAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Article
  3. Organically Modified Mesoporous Silica Nanoparticles against Bacterial Resistance.Chemistry of materials : a publication of the American Chemical Society · 2023
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Impact of the antibiotic-cargo from MSNs on Gram-positive and Gram-negative bacterial biofilms.Microporous and mesoporous materials : the official journal of the International Zeolite Association · 2021
    Article
  13. Review
  14. Review
  15. Review
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  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nanjing HaoDepartment of Chemistry, University of Massachusetts, Lowell, MA, 01854, USA.
Xuan ChenDepartment of Chemistry, University of Massachusetts, Lowell, MA, 01854, USA.
Seaho JeonDepartment of Chemistry, University of Massachusetts, Lowell, MA, 01854, USA.
Mingdi YanDepartment of Chemistry, University of Massachusetts, Lowell, MA, 01854, USA.

Funding

Photogenerated Carbohydrate MicroarraysR01GM080295 · NIGMS · UNIVERSITY OF MASSACHUSETTS LOWELL · PI YAN, MINGDI · 2008 to 2012
$2.0M
Maltoheptaose based nanotherapeutics for multidrug resistant bacterial infectionR21AI109896 · NIAID · UNIVERSITY OF MASSACHUSETTS LOWELL · PI YAN, MINGDI · 2014 to 2015
$444k
NIAID NIH HHS 1R21AI109896-01NIAID NIH HHS R21 AI109896NIGMS NIH HHS R01 GM080295NIGMS NIH HHS R01GM080295
6 · The paper itself

Abstract

Engineering nanomaterials with enhanced antibacterial activities remains a critical and practical challenge. Hollow oblate mesoporous silica nanoparticles (HOMSNs) are synthesized by a simple protocol of ammonia hydrothermal treatment of oblate mesoporous silica nanoparticles prepared using dibenzyl ether as a cosolvent. When conjugated with trehalose as the targeting ligand, the antibiotic-encapsulated HOMSNs exhibit high binding affinity and antibacterial efficacy toward mycobacteria.

Indexed as

Anti-Bacterial AgentsCarbohydratesIsoniazidMetal NanoparticlesMycobacteriumNanospheresPorositySilicon DioxideAnti-Bacterial AgentsCarbohydratesIsoniazidSilicon Dioxideantimicrobialmesoporous silica nanoparticlesnanoantibioticstargetingtrehalose

Identifiers

PMID26450697
PMCPMC4701626

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.