SynthesisDer Orthopade2016
[The time-related risk for knee osteoarthritis after ACL injury. Results from a systematic review].
Synthesis in Der Orthopade, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Age-moderating effects and training characteristics of neuromuscular training for preventing knee injuries: a systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- Management after acute rupture of the anterior cruciate ligament (ACL). Part 1: ACL reconstruction has a protective effect on secondary meniscus and cartilage lesions.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Review
- [New assessment recommendations for disability in private accident insurance, part 1 : An interdisciplinary consented approach-Basics].Der Unfallchirurg · 2022Review
- Conversion rates and timing to total knee arthroplasty following anterior cruciate ligament reconstruction: a US population-based study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2022Article
- Knee injuries concomitant to posterior acetabular fractures: an association to look for.International orthopaedics · 2021Article
- [Osteoarthritis classifications : Modification proposal for the criteria of Kellgren and Vallotton].Der Radiologe · 2019Review
- [Incidence of knee injuries : Numbers for outpatient and inpatient care in Germany].Der Orthopade · 2016Article
- [Prognostic assessment in private healthcare insurance part 1 : Risk of osteoarthritis].Der Unfallchirurg · 2016Article
- Long-term outcome of anterior cruciate ligament tear without reconstruction: a longitudinal prospective study.International orthopaedics · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe aim of this review was to evaluate the time-related risk for knee osteoarthritis in patients after ACL injury. MATERIALS AND
methodsThe primary search was carried out in different medical databases with the deadline 12.01.2014. The search strategy for the evaluation was [ACL] AND [osteoarthritis] including "all fields". All 1656 title/abstracts were reviewed by two independent researchers who selected 140 papers for full text review. Finally, a total of 21 relevant publications were identified for inclusion in this current paper.
resultsThe incidence of knee osteoarthritis rises significantly over time. Two years after injury it was 6.9%, after 5 years 32.2%, after 7 years 36.3%, and after 10 years 79.6%. At the same time, the crude relative risk of OA rises as the time interval since injury increases. The relative risk of OA has already doubled by 2 years after ACL injury). By 7 years it has increased fivefold and compared with OA status at the time of injury it is still increasing significantly after 10 years.
conclusionsThe ACL injury is a significant risk factor for the development of early-onset secondary knee osteoarthritis. Within 5 years of the injury the knee shows clear signs of osteoarthritis on MRI. However, these lesions are often not associated with any clinical signs. Knee osteoarthritis as a severe disease starts 8 years or later after the injury, when it requires treatment.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.