ArticleScientific reports2015
Ca(2+)-regulated cyclic electron flow supplies ATP for nitrogen starvation-induced lipid biosynthesis in green alga.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 76 citations in OpenAlex.
- Charting the state of GEMs in microalgae: progress, challenges, and innovations.Frontiers in plant science · 2025Review
- Regulation of Microalgal Photosynthetic Electron Transfer.Plants (Basel, Switzerland) · 2024Review
- Characterization of the Wave Phenomenon in Flash-Induced Fluorescence Relaxation and Its Application to Study Cyclic Electron Pathways in Microalgae.International journal of molecular sciences · 2022Article
- The significance of calcium-sensing receptor in sustaining photosynthesis and ameliorating stress responses in plants.Frontiers in plant science · 2022Review
- Starch Production inCells · 2021Article
- High nitrogen inhibits photosynthetic performance in a shade-tolerant and N-sensitive species Panax notoginseng.Photosynthesis research · 2021Article
- Lipid Remodeling Reveals the Adaptations of a Marine Diatom to Ocean Acidification.Frontiers in microbiology · 2021Article
- An Overview of Potential Oleaginous Microorganisms and Their Role in Biodiesel and Omega-3 Fatty Acid-Based Industries.Microorganisms · 2020Review
- Low-Temperature Adaptation of the Snow AlgaFrontiers in microbiology · 2020Article
- Metabolic Insights Into Infochemicals Induced Colony Formation and Flocculation inFrontiers in microbiology · 2020Article
- Time-resolved multi-omics analysis reveals the role of nutrient stress-induced resource reallocation for TAG accumulation in oleaginous fungusBiotechnology for biofuels · 2020Article
- Subcellular Energetics and Carbon Storage inCells · 2019Review
- Deesterification of astaxanthin and intermediate esters fromBiotechnology reports (Amsterdam, Netherlands) · 2019Article
- A kinetic metabolic study of lipid production in Chlorella protothecoides under heterotrophic condition.Microbial cell factories · 2019Article
- Review
- Comparative metabolic profiling of the lipid-producing green microalgaBiotechnology for biofuels · 2017Article
- Time-resolved transcriptome analysis and lipid pathway reconstruction of the oleaginous green microalgaBiotechnology for biofuels · 2017Article
- Saturating Light Induces Sustained Accumulation of Oil in Plastidal Lipid Droplets in Chlamydomonas reinhardtii.Plant physiology · 2016Article
- Improved Productivity of Neutral Lipids in Chlorella sp. A2 by Minimal Nitrogen Supply.Frontiers in microbiology · 2016Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We previously showed that both the linear photosynthetic electron transportation rate and the respiration rate dropped significantly during N starvation-induced neutral lipid accumulation in an oil-producing microalga, Chlorella sorokiniana, and proposed a possible role for cyclic electron flow (CEF) in ATP supply. In this study, we further exploited this hypothesis in both Chlorella sorokiniana C3 and the model green alga Chlamydomonas. We found that both the rate of CEF around photosystem I and the activity of thylakoid membrane-located ATP synthetase increased significantly during N starvation to drive ATP production. Furthermore, we demonstrated that the Chlamydomonas mutant pgrl1, which is deficient in PGRL1-mediated CEF, accumulated less neutral lipids and had reduced rates of CEF under N starvation. Further analysis revealed that Ca(2+) signaling regulates N starvation-induced neutral lipid biosynthesis in Chlamydomonas by increasing calmodulin activity and boosting the expression of the calcium sensor protein that regulates Pgrl1-mediated CEF. Thus, Ca(2+)-regulated CEF supplies ATP for N starvation-induced lipid biosynthesis in green alga. The increased CEF may re-equilibrate the ATP/NADPH balance and recycle excess light energy in photosystems to prevent photooxidative damage, suggesting Ca(2+)-regulated CEF also played a key role in protecting and sustaining photosystems.
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