Evidence map›Paper›PMID 26449986›Full record

ArticleBMC neurology2015

Enterprise stent for the treatment of symptomatic intracranial atherosclerotic stenosis: an initial experience of 44 patients.

Zhengzhe Feng, Guoli Duan, Ping Zhang, Lei Chen, Yi Xu, Bo Hong, Wenyuan Zhao, Jianmin Liu, Qinghai Huang

Open access · goldAbstract read
In one paragraph

Article in BMC neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 4 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 4 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Pooled it
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  5. Optional or optimal? off-label stenting for intracranial atherosclerotic stenosis: A scoping review.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
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  7. Short-term outcome of stenting with Enterprise stents for symptomatic intracranial atherosclerotic disease at a single center.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2023
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  16. A novel technique for stenting of intracranial stenosis using the Neuroform Atlas stent and Gateway balloon catheter.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Zhengzhe FengDepartment of Neurosurgery, Changhai Hospital, Second Military Medical University, 168 Changhai Rd, Shanghai, 200433, China. shchfzz@163.com.
Guoli DuanDepartment of Neurosurgery, Changhai Hospital, Second Military Medical University, 168 Changhai Rd, Shanghai, 200433, China. 974714225@qq.com.
Ping ZhangDepartment of Neurosurgery, Changhai Hospital, Second Military Medical University, 168 Changhai Rd, Shanghai, 200433, China. pingzhang1121@163.com.
Lei ChenDepartment of Neurosurgery, Changhai Hospital, Second Military Medical University, 168 Changhai Rd, Shanghai, 200433, China. gloria_leilei@163.com.
Yi XuDepartment of Neurosurgery, Changhai Hospital, Second Military Medical University, 168 Changhai Rd, Shanghai, 200433, China. xuyichyy@163.com.
Bo HongDepartment of Neurosurgery, Changhai Hospital, Second Military Medical University, 168 Changhai Rd, Shanghai, 200433, China. hongbosmmu@vip.126.com.
Wenyuan ZhaoDepartment of Neurosurgery, Changhai Hospital, Second Military Medical University, 168 Changhai Rd, Shanghai, 200433, China. doczhaowy@163.com.
Jianmin LiuDepartment of Neurosurgery, Changhai Hospital, Second Military Medical University, 168 Changhai Rd, Shanghai, 200433, China. liu118@vip.163.com.
Qinghai HuangDepartment of Neurosurgery, Changhai Hospital, Second Military Medical University, 168 Changhai Rd, Shanghai, 200433, China. shchfzz141012@163.com.
Changhai Hospital · CNSecond Military Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWingspan stenting for the treatment of complex intracranial atherosclerotic stenosis (ICAS), i.e., that involving tortuous vascular pathways, long (>15 mm) lesions or arterial bifurcations, has a relatively high risk of complications. This retrospective study assessed the safety and efficacy of undersized balloon angioplasty followed by deployment of the more flexible Enterprise stent for the treatment of complex symptomatic ICAS.

methodsForty-four patients on combined antiplatelet therapy and intensive risk factor management and a symptomatic 70-99% stenosis of a major intracranial artery in complex settings that was treated with balloon angioplasty and Enterprise stent deployment between July 2009 and August 2013 were enrolled. Primary outcome was occurrence of ischemic or hemorrhagic stroke or death within 30 days after intervention. Secondary outcomes included procedural success (defined as achievement of <50% immediate residual stenosis), and follow-up clinical and angiographic outcomes.

resultsWith a procedural success rate of 100%, stenosis was reduced from 79.3 ± 8.1-14.9 ± 2.3%. Three (6.8%) ischemic and 1 (2.2%) hemorrhagic strokes occurred during the periprocedural period, with no further transient ischemic attacks or strokes in the 42 patients available at median 25.6 (range, 12-57) months follow-up. Of the 38 (86.4%) patients who underwent angiographic follow-up, 3 (6.81%) developed >50% in-stent restenosis after mean 22 months follow-up.

conclusionIn this retrospective, single-center experience, undersized balloon angioplasty followed by Enterprise stent deployment appears technically feasible with a relatively low rate of complications for the treatment of complex symptomatic ICAS. Prospective, multicenter, randomized controlled trials against optimal medical management are warranted.

Indexed as

Angioplasty, BalloonStentsAdultAgedArterial Occlusive DiseasesFemaleFollow-Up StudiesHumansIntracranial ArteriosclerosisMaleMiddle AgedRetrospective StudiesStroke

Identifiers

PMID26449986
PMCPMC4598959
OpenAlexW1930060694

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.