Evidence map›Paper›PMID 26449841›Full record

ReviewCurrent oncology reports2015

The Role of Radiotherapy After Radical Prostatectomy in Patients with Prostate Cancer.

Giorgio Gandaglia, Cesare Cozzarini, Alexandre Mottrie, Alberto Bossi, Nicola Fossati, Francesco Montorsi, Alberto Briganti

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current oncology reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Functional and oncological outcomes of salvage external beam radiotherapy following robot-assisted radical prostatectomy in a Canadian cohort.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Giorgio GandagliaUnit of Urology/Division of Oncology, URI, IRCCS Ospedale San Raffaele, Milan, Italy. giorgio.gandaglia@gmail.com.
Cesare CozzariniDepartment of Radiotherapy, IRCCS Ospedale San Raffaele, Milan, Italy.
Alexandre MottrieOLV Vattikuti Robotic Surgery Institute, Melle, Belgium.
Alberto BossiDepartment of Radiation Oncology, Institut Gustave Roussy, Villejuif, France.
Nicola FossatiUnit of Urology/Division of Oncology, URI, IRCCS Ospedale San Raffaele, Milan, Italy.
Francesco MontorsiUnit of Urology/Division of Oncology, URI, IRCCS Ospedale San Raffaele, Milan, Italy.
Alberto BrigantiUnit of Urology/Division of Oncology, URI, IRCCS Ospedale San Raffaele, Milan, Italy.
IRCCS Ospedale San Raffaele · ITInstitut Gustave Roussy · FRORSI Academy · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A non-negligible proportion of prostate cancer (PCa) patients undergoing radical prostatectomy (RP) harbors aggressive disease. These individuals are at higher risk of experiencing recurrence after surgery. Results from prospective, randomized trials support the efficacy of adjuvant radiotherapy (aRT) on cancer control in selected patients with adverse disease features at RP. However, only one of these randomized trials found a significant benefit of aRT on survival. Although such a level of evidence is not currently available for salvage RT, retrospective studies demonstrated that this approach leads to excellent outcomes if administered at the earliest sign of PSA recurrence. Prognostic models might help clinicians in identifying patients who would benefit the most from adjuvant and/or salvage RT. This individualized approach would allow sparing the risk of short- and long-term toxicity in a substantial proportion of patients. Nonetheless, results from randomized trials are still awaited to compare the efficacy of (early) salvage and aRT.

Indexed as

ProstatectomyHumansMaleNeoplasm Recurrence, LocalProstatic NeoplasmsRadiotherapy, AdjuvantRetrospective StudiesSalvage TherapyAdjuvant radiotherapyAndrogen deprivation therapyMulti-modal treatmentProstate cancerRadical prostatectomySalvage radiotherapy

Identifiers

PMID26449841
OpenAlexW1962187970

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.