Evidence map›Paper›PMID 26449562›Full record

ArticleEuropean radiology2016

Parotid gland tumours: MR tractography to assess contact with the facial nerve.

Arnaud Attyé, Alexandre Karkas, Irène Troprès, Matthieu Roustit, Adrian Kastler, Georges Bettega, Laurent Lamalle, Félix Renard, Christian Righini, Alexandre Krainik

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Article in European radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Arnaud AttyéDepartment of Neuroradiology and MRI, Grenoble University Hospital - SFR RMN Neurosciences, Grenoble, France. aattye@chu-grenoble.fr.
Alexandre KarkasDepartment of Otolaryngology-Head and Neck Surgery, University Hospital of Grenoble, Grenoble, France.
Irène TroprèsInserm, US 17, Grenoble, France.
Matthieu RoustitDepartment of Statistics, University Hospital of Grenoble, Grenoble, France.
Adrian KastlerDepartment of Neuroradiology and MRI, Grenoble University Hospital - SFR RMN Neurosciences, Grenoble, France.
Georges BettegaDepartment of Maxillofacial Surgery, University Hospital of Grenoble, Grenoble, France.
Laurent LamalleInserm, US 17, Grenoble, France.
Félix RenardUniversity Grenoble Alpes, IRMaGe, F-38000, Grenoble, France.
Christian RighiniDepartment of Otolaryngology-Head and Neck Surgery, University Hospital of Grenoble, Grenoble, France.
Alexandre KrainikDepartment of Neuroradiology and MRI, Grenoble University Hospital - SFR RMN Neurosciences, Grenoble, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the feasibility of intraparotid facial nerve (VIIn) tractographic reconstructions in estimating the presence of a contact between the VIIn and the tumour, in patients requiring surgical resection of parotid tumours.

methodsPatients underwent MR scans with VIIn tractography calculated with the constrained spherical deconvolution model. The parameters of the diffusion sequence were: b-value of 1000 s/mm(2); 32 directions; voxel size: 2 mm isotropic; scan time: 9'31'. The potential contacts between VIIn branches and tumours were estimated with different initial fractional anisotropy (iFA) cut-offs compared to surgical data. Surgeons were blinded to the tractography reconstructions and identified both nerves and contact with tumours using nerve stimulation and reference photographs.

resultsTwenty-six patients were included in this study and the mean patient age was 55.2 years. Surgical direct assessment of VIIn allowed identifying 0.1 as the iFA threshold with the best sensitivity to detect tumour contact. In all patients with successful VIIn identification by tractography, surgeons confirmed nerve courses as well as lesion location in parotid glands. Mean VIIn branch FA values were significantly lower in cases with tumour contact (t-test; p ≤ 0.01).

conclusionsThis study showed the feasibility of intraparotid VIIn tractography to identify nerve contact with parotid tumours. KEY POINTS: • Diffusion imaging is an efficient method for highlighting the intraparotid VIIn. • Visualization of the VIIn may help to better manage patients before surgery. • We bring new insights to future trials for patients with VIIn dysfunction. • We aimed to provide radio-anatomical references for further studies.

Indexed as

AdenolymphomaAdenoma, OxyphilicAdenoma, PleomorphicCarcinoma, Adenoid CysticCystsDiffusion Tensor ImagingFacial NerveFeasibility StudiesFemaleHumansImage Processing, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance ImagingMaleMiddle AgedParotid DiseasesDiffusion tractographyFacial nerveMagnetic resonance imagingParotid glandSalivary gland neoplasms

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.