Evidence map›Paper›PMID 26449421›Full record

ReviewInternational journal of obesity (2005)2016

The importance of prediction model validation and assessment in obesity and nutrition research.

A E Ivanescu, P Li, B George, A W Brown, S W Keith, D Raju, D B Allison

Abstract readReview
In one paragraph

Review in International journal of obesity (2005), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

A E IvanescuDepartment of Mathematical Sciences, Montclair State University, Montclair, NJ, USA.
P LiOffice of Energetics and Nutrition Obesity Research Center, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0000-0002-9026-9999
B GeorgeOffice of Energetics and Nutrition Obesity Research Center, University of Alabama at Birmingham, Birmingham, AL, USA.
A W BrownOffice of Energetics and Nutrition Obesity Research Center, University of Alabama at Birmingham, Birmingham, AL, USA.
S W KeithDivision of Biostatistics, Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA, USA.
D RajuSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
D B AllisonOffice of Energetics and Nutrition Obesity Research Center, University of Alabama at Birmingham, Birmingham, AL, USA.

Funding

Why is the prevalence of obesity so high in U.S. Southern States? Regional predictors of BMI and obesity treatment response.P30DK056336 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2000 to 2026
$31.9M
Strengthening Causal Inference in Behavioral Obesity ResearchR25HL124208 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ALLISON, DAVID B, BROWN, ANDREW W · 2014 to 2023
$1.8M
The Mathematical Sciences in Obesity ResearchR25DK099080 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DAVID B ALLISON, Andrew W Brown · 2013 to 2026
$1.2M
NHLBI NIH HHS R25 HL124208NIDDK NIH HHS P30 DK056336NIDDK NIH HHS R25 DK099080
6 · The paper itself

Abstract

Deriving statistical models to predict one variable from one or more other variables, or predictive modeling, is an important activity in obesity and nutrition research. To determine the quality of the model, it is necessary to quantify and report the predictive validity of the derived models. Conducting validation of the predictive measures provides essential information to the research community about the model. Unfortunately, many articles fail to account for the nearly inevitable reduction in predictive ability that occurs when a model derived on one data set is applied to a new data set. Under some circumstances, the predictive validity can be reduced to nearly zero. In this overview, we explain why reductions in predictive validity occur, define the metrics commonly used to estimate the predictive validity of a model (for example, coefficient of determination (R(2)), mean squared error, sensitivity, specificity, receiver operating characteristic and concordance index) and describe methods to estimate the predictive validity (for example, cross-validation, bootstrap, and adjusted and shrunken R(2)). We emphasize that methods for estimating the expected reduction in predictive ability of a model in new samples are available and this expected reduction should always be reported when new predictive models are introduced.

Indexed as

ObesityBiomedical ResearchHumansModels, StatisticalNutritional SciencesPredictive Value of TestsReproducibility of Results

Identifiers

PMID26449421
PMCPMC4826636

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.