Evidence map›Paper›PMID 26449181›Full record

ReviewProteomics2016

Exploring the potential of public proteomics data.

Marc Vaudel, Kenneth Verheggen, Attila Csordas, Helge Raeder, Frode S Berven, Lennart Martens, Juan A Vizcaíno, Harald Barsnes

Abstract readReview
In one paragraph

Review in Proteomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  19. A Second Look at FAIR in Proteomic Investigations.Journal of proteome research · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marc VaudelProteomics Unit, Department of Biomedicine, University of Bergen, Bergen, Norway.
Kenneth VerheggenMedical Biotechnology Center, VIB, Ghent, Belgium.
Attila CsordasEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.
Helge RaederDepartment of Clinical Science, KG Jebsen Center for Diabetes Research, University of Bergen, Bergen, Norway.
Frode S BervenProteomics Unit, Department of Biomedicine, University of Bergen, Bergen, Norway.
Lennart MartensMedical Biotechnology Center, VIB, Ghent, Belgium.
Juan A VizcaínoEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.
Harald BarsnesProteomics Unit, Department of Biomedicine, University of Bergen, Bergen, Norway.

Funding

Biotechnology and Biological Sciences Research Council BB/L024225/1Wellcome TrustWellcome Trust WT101477MA
6 · The paper itself

Abstract

In a global effort for scientific transparency, it has become feasible and good practice to share experimental data supporting novel findings. Consequently, the amount of publicly available MS-based proteomics data has grown substantially in recent years. With some notable exceptions, this extensive material has however largely been left untouched. The time has now come for the proteomics community to utilize this potential gold mine for new discoveries, and uncover its untapped potential. In this review, we provide a brief history of the sharing of proteomics data, showing ways in which publicly available proteomics data are already being (re-)used, and outline potential future opportunities based on four different usage types: use, reuse, reprocess, and repurpose. We thus aim to assist the proteomics community in stepping up to the challenge, and to make the most of the rapidly increasing amount of public proteomics data.

Indexed as

ProteomicsAnimalsComputational BiologyDatabases, ProteinHumansInformation DisseminationKnowledge BasesMolecular Sequence AnnotationProtein Processing, Post-TranslationalBioinformaticsComputational proteomicsData analysisDatabasesData standards

Identifiers

PMID26449181
PMCPMC4738454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.