ReviewJournal of the American College of Cardiology2015
Arrhythmia-Induced Cardiomyopathies: Mechanisms, Recognition, and Management.
Review in Journal of the American College of Cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05442203 (Electrocardiogram-based Artificial Intelligence-assisted Detection of Heart Disease), which is not on this map. Cited by 160 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Electrocardiogram-based Artificial Intelligence-assisted Detection of Heart Disease
Who cites it
160 citing papers in PubMed, 5 syntheses or guidelines pooled it, 363 citations in OpenAlex.
- Guideline
- 2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.Journal of the American College of Cardiology · 2024Guideline
- Heart failure and atrial flutter: a systematic review of current knowledge and practices.ESC heart failure · 2021Pooled it
- Catheter ablation versus conventional treatment of atrial fibrillation in patients with heart failure with reduced ejection fraction: a systematic review and meta-analysis of randomized controlled trials.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2018Pooled it
- Pooled it
- Right Ventricular Systolic Dysfunction Predicts Recovery of Left Ventricular Systolic Function and Reduced Quality of Life in Patients With Arrhythmia-Induced Cardiomyopathy.Clinical cardiology · 2025Trial
- Confirm Rx insertable cardiac monitor for primary atrial fibrillation detection in high-risk heart failure patients (Confirm-AF trial).Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2023Trial
- Understanding the Mortality Trends in Patients With Ventricular Arrhythmias and Cardiomyopathy: A 25-Year Retrospective Analysis From 1999-2024.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026Observational
- Left Atrial Appendage Occlusion for Persistent Thrombus Preventing Rhythm Control.JACC. Case reports · 2026Article
- When Virchow's Triad Goes on Overdrive: Catastrophic Multi-System Thrombosis in the Setting of New-Onset Heart Failure in a Previously Healthy Man.Journal of medical cases · 2026Article
- Myocardial Function Assessment After Cardioversion in Persistent Atrial Fibrillation: Current Evidence and Future Directions.Diagnostics (Basel, Switzerland) · 2026Review
- Utility of Post-Procedural HFA-PEFF Reassessment for Long-Term Heart Failure Risk Stratification After Atrial Fibrillation Ablation.Journal of arrhythmia · 2026Article
- Arrhythmia and cardiomyopathy risk in Taiwan with complementary biobank evidence on thyroid genetic susceptibility: an integrative population-based framework.Endocrine connections · 2026Article
- Association of Myocardial Degeneration With Delayed Recovery of Left Ventricular Function in Atrial Fibrillation-Induced Cardiomyopathy.Circulation reports · 2026Article
- Prevalence and Recovery of Arrhythmia-Induced Cardiomyopathy in Patients With Newly Diagnosed Heart Failure Using a Wearable Defibrillator: A Real-World Cohort Study.Journal of cardiovascular electrophysiology · 2026Article
- Ventricular preexcitation-induced subclinical LV dysfunction: Insights from pressure-strain loop imaging.American heart journal plus : cardiology research and practice · 2026Article
- Computed Tomography-Derived Left Ventricular Extracellular Volume Predicts Reverse Remodeling After Catheter Ablation for Atrial Fibrillation.Journal of cardiovascular development and disease · 2026Article
- Delayed Efficacy of Radiofrequency Catheter Ablation in Intramural Ventricular Arrhythmias: Implications for Timing of Repeat Ablation and ICD Implantation.Clinical case reports · 2026Article
- When the Beat Breaks the Heart: A Case of Arrhythmia-Induced Mid-ventricular Takotsubo Cardiomyopathy.Cureus · 2026Article
- Tachycardia-Mediated Cardiomyopathy from Concealed Left-Sided AVRT with Complete Recovery Post-Ablation.Oxford medical case reports · 2026Article
100 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 6 institutions in 1 country.
Funding
Abstract
Arrhythmia-induced cardiomyopathy (AIC) is a potentially reversible condition in which left ventricular dysfunction is induced or mediated by atrial or ventricular arrhythmias. Cellular and extracellular changes in response to the culprit arrhythmia have been identified, but specific pathophysiological mechanisms remain unclear. Early recognition of AIC and prompt treatment of the culprit arrhythmia using pharmacological or ablative techniques result in symptom resolution and recovery of ventricular function. Although cardiomyopathy in response to an arrhythmia may take months to years to develop, recurrent arrhythmia can result in rapid decline in ventricular function with development of heart failure, suggesting residual ultrastructural abnormalities. Reports of sudden death in patients with normalized left ventricular ejection fraction cast doubt on the complete reversibility of this condition. Several aspects of AIC, including specific pathophysiological mechanisms, predisposing factors, optimal therapeutic strategies to prevent ultrastructural changes, and long-term risk of sudden death remain unresolved and need further research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.