Evidence map›Paper›PMID 26448658›Full record

ArticleHospital pharmacy2015

Impact of Drug Shortages on Health System Pharmacies in the Southeastern United States.

Celeste R Caulder, Brenna Mehta, P Brandon Bookstaver, LaVetra D Sims, Bill Stevenson

Open access · greenAbstract read
In one paragraph

Article in Hospital pharmacy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
14.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 75 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Exploring Drug Shortages in the United Kingdom.Pharmacy (Basel, Switzerland) · 2023
    Article
  7. Article
  8. Medicine shortages: impact behind numbers.Journal of pharmaceutical policy and practice · 2023
    Article
  9. Article
  10. Article
  11. Drug shortages in low- and middle-income countries: Colombia as a case study.Journal of pharmaceutical policy and practice · 2022
    Article
  12. Community Pharmacy Staff Knowledge, Opinion and Practice toward Drug Shortages in Saudi Arabia.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021
    Article
  13. Article
  14. Review
  15. Results of EAHP's 2019 Medicines Shortages Survey.European journal of hospital pharmacy : science and practice · 2020
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Cyberbiosecurity in Advanced Manufacturing Models.Frontiers in bioengineering and biotechnology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Celeste R CaulderAssistant Professor, Department of Clinical Pharmacy and Outcomes Sciences, South Carolina College of Pharmacy, University of South Carolina , Columbia, South Carolina.
Brenna MehtaDrug Information, Palmetto Health Richland , Columbia, South Carolina.
P Brandon BookstaverAssociate Professor and Vice Chair, Department of Clinical Pharmacy and Outcomes Sciences, South Carolina College of Pharmacy, University of South Carolina , Columbia, South Carolina.
LaVetra D SimsPGY-1 Pharmacy Resident, Carolinas Medical Center , Charlotte, North Carolina.
Bill StevensonDirector of Pharmacy Services, Oconee Medical Center, Seneca , South Carolina.
University of South Carolina · USCarolinas Medical Center · USPalmetto Health Richland · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDrug shortages have become all too common and affect all aspects of the health care delivery system. The increased number of drug shortages has had a negative impact on patient care as well as costly financial implications.

objectivesThis article identifies the current problems and negative outcomes drug shortages have caused and provides a framework for how to best prepare for and combat future shortages. It highlights specific problems faced by health care system pharmacies in the Southeastern United States and the managerial responses to address these shortage situations.

methodsA 34-question, multiple-choice survey was distributed to pharmacy directors in North Carolina, South Carolina, Georgia, and Florida.

resultsOf 549 surveys distributed, 219 (40%) responses were received. Respondents reported that drug shortages cause 1% to 5% error rates in hospitals and that 60% of the time drug shortages create unsafe conditions for patients and staff. Many of the respondents reported a 300% to 500% markup on medications on the shortage list. Seventy-six percent of institutions have autosubstitutions for drug shortages that have been preapproved by Pharmacy & Therapeutics Committees.

conclusionsThe causes of drug shortages are multifaceted, and the safety and financial implications can be costly. In the short term, health care institutions can utilize pharmacists to assist in circumventing the drug shortage problem. The combined efforts of all health care professionals, the US government, manufacturers, and the lay public are necessary to bring awareness and plausible solutions to the drug shortage problems in the long term.

Indexed as

drug shortagemedication errorprice gauging

Identifiers

PMID26448658
PMCPMC4589883
OpenAlexW2011142098

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.