ArticleTissue engineering. Part B, Reviews2016
The Tissue-Engineered Vascular Graft-Past, Present, and Future.
Article in Tissue engineering. Part B, Reviews, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 301 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
301 citing papers in PubMed, 765 citations in OpenAlex.
- Sheep in vivo models for evaluation of safety, functionality and regenerative potential of arterial grafts.MethodsX · 2026Article
- Revisiting the tension-free paradigm: Axially prestretched elastomeric nanofibrillar grafts restore artery-like axial biomechanics in a preclinical model.Acta biomaterialia · 2026Article
- Induced Pluripotent Stem Cell-Derived Small-Diameter Vascular Grafts: Scaffold Design, Immune Engineering, and Clinical Translation.Journal of cellular physiology · 2026Review
- Structural Motifs as Programmable Design Parameters for Tuning Vascular Mechanics in Fiber-Reinforced Hydrogel Grafts.Biomimetics (Basel, Switzerland) · 2026Article
- Image-Based CFD Analysis of Blood Flow in Non-Porous and Porous Prosthetic Vascular Grafts.Bioengineering (Basel, Switzerland) · 2026Article
- Biomimetic Vascular Scaffold with Seamless Electrospun Aligned Nanofiber Conduit and 3D-Printed Coil Reinforcement.Advanced healthcare materials · 2026Article
- Application of Transgenic Silk Fibroin to Biomaterials.Biotechnology and bioengineering · 2026Review
- Spontaneous Helical Alignment of Smooth Muscle Cells to Form a Medial Layer for Engineered Microvasculature.Advanced healthcare materials · 2026Article
- Pre-Wetting Reduces Blood Component Deposition on Polyvinyl Alcohol-Coated Poly-ε-Caprolactone Nanofiber Grafts.Bioengineering (Basel, Switzerland) · 2026Article
- Bacterial nanocellulose: biosynthesis, structural properties and vascular tissue engineering applications.Journal of materials science. Materials in medicine · 2026Review
- Evolutions in Cardiovascular Implants-A Review of Past, Present, and Future.Micromachines · 2026Review
- Article
- Copolymers of Poly(Butylene Trans-1,4-Cyclohexanedicarboxylate)/Pripol as New Biomaterial Platform for Small Diameter Vascular Graft.Advanced healthcare materials · 2026Article
- An IoT-Enabled Modular 3D Bioreactor for Vascular Tissue Engineering: Design, Fabrication, and Biological Validation.Bioengineering (Basel, Switzerland) · 2026Article
- Tunable Bioresorbable Scaffolds With Marine Sulfated Polysaccharides for Small-Caliber Vascular Grafts: A Multi-Layered Strategy Combining Electrospinning and 4-Axis Printing.Advanced healthcare materials · 2026Article
- Generation of Fibrin-Based Aortic Vessels with Layer-Specific Cell Architecture Under Pulsatile Perfusion in a Clinical Organ Care System.Annals of biomedical engineering · 2026Article
- Reinforced biotubes as readily available and regenerative vascular grafts.Nature communications · 2026Article
- Implantation of Bioreactor-Conditioned Plant-Based Vascular Grafts.Journal of functional biomaterials · 2026Article
- The LITA-LAD coronary bypass: historical perfection with emerging future perspectives in the third millennium.Frontiers in cardiovascular medicine · 2026Article
- Exploring Perivascular Adipose Tissue Responses to Bioresorbable Thermoplastic Polyurethane Vascular Grafts.Biomaterials research · 2026Article
241 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiovascular disease is the leading cause of death worldwide, with this trend predicted to continue for the foreseeable future. Common disorders are associated with the stenosis or occlusion of blood vessels. The preferred treatment for the long-term revascularization of occluded vessels is surgery utilizing vascular grafts, such as coronary artery bypass grafting and peripheral artery bypass grafting. Currently, autologous vessels such as the saphenous vein and internal thoracic artery represent the gold standard grafts for small-diameter vessels (<6 mm), outperforming synthetic alternatives. However, these vessels are of limited availability, require invasive harvest, and are often unsuitable for use. To address this, the development of a tissue-engineered vascular graft (TEVG) has been rigorously pursued. This article reviews the current state of the art of TEVGs. The various approaches being explored to generate TEVGs are described, including scaffold-based methods (using synthetic and natural polymers), the use of decellularized natural matrices, and tissue self-assembly processes, with the results of various in vivo studies, including clinical trials, highlighted. A discussion of the key areas for further investigation, including graft cell source, mechanical properties, hemodynamics, integration, and assessment in animal models, is then presented.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.